Bilateral collicular interaction: Modulation of auditory signal processing in frequency domain

Cheng, Liang; Mei, Hui-Xian; Tang, Jia; Fu, Zi-Ying; Jen, Philip H.‐S.; Chen, Q.-C.

doi:10.1016/j.neuroscience.2013.01.011

Cited by 12 publications

(10 citation statements)

References 66 publications

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“…We are uncertain if this discrepancy in observation is simply due to sampling bias or functions of the different auditory centers. In our previous study on the intercollicular effects on frequency domain, focal IC ES electrical stimulation produced corticofugal-like modulation on the BF shift of IC Mdu neurons [ 27 ]. Considering that tone is a quality of particular importance in discriminating sound signals in nature, we suggest that modulation of intercollicular effects at the subcortical level is more responsible for frequency than for MT, which represents the auditory sensitivity of neurons.…”

Section: Discussionmentioning

confidence: 99%

Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice

Mei

Tang

et al. 2016

Neural Plasticity

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In the auditory pathway, the commissure of the inferior colliculus (IC) interconnects the two ICs on both sides of the dorsal midbrain. This interconnection could mediate an interaction between the two ICs during sound signal processing. The intercollicular effects evoked by focal electric stimulation for 30 min could inhibit or facilitate auditory responses and induce plastic changes in the response minimum threshold (MT) of IC neurons. Changes in MT are dependent on the best frequency (BF) and MT difference. The MT shift is larger in IC neurons with BF differences ≤2 kHz than in those with BF differences >2 kHz. Moreover, MTs that shift toward electrically stimulated IC neurons increase with the increasing MT difference between the two ICs. The shift in MT lasts for a certain period of time and then returns to previous levels within ~150 min. The collicular interactions are either reciprocal or unilateral under alternate stimulating and recording conditions in both ICs. Our results suggest that intercollicular effects may be involved in the acoustic experience-dependent plasticity of the MT of IC neurons.

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Section: Discussionmentioning

confidence: 99%

Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice

Mei

Tang

et al. 2016

Neural Plasticity

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“…The surgical procedures were basically the same as described in our previous studies [26–28]. Briefly, after being anesthetized with Nembutal (60–90 mg/kg b.…”

Section: Methodsmentioning

confidence: 99%

Long-Term Impairment of Sound Processing in the Auditory Midbrain by Daily Short-Term Exposure to Moderate Noise

et al. 2017

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Most citizen people are exposed daily to environmental noise at moderate levels with a short duration. The aim of the present study was to determine the effects of daily short-term exposure to moderate noise on sound level processing in the auditory midbrain. Sound processing properties of auditory midbrain neurons were recorded in anesthetized mice exposed to moderate noise (80 dB SPL, 2 h/d for 6 weeks) and were compared with those from age-matched controls. Neurons in exposed mice had a higher minimum threshold and maximum response intensity, a longer first spike latency, and a higher slope and narrower dynamic range for rate level function. However, these observed changes were greater in neurons with the best frequency within the noise exposure frequency range compared with those outside the frequency range. These sound processing properties also remained abnormal after a 12-week period of recovery in a quiet laboratory environment after completion of noise exposure. In conclusion, even daily short-term exposure to moderate noise can cause long-term impairment of sound level processing in a frequency-specific manner in auditory midbrain neurons.

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“…(Modified from Orton and Rees, 2014. ) Figure 4 near here Electrical stimulation of one IC leads to changes in firing rate and broadening or narrowing of V-shaped tuning curves for neurons in the other IC, in some cases accompanied by a change in best frequency (Mei et al 2012a;Cheng et al 2013). The direction of such changes depended on the difference between the frequency represented by the stimulation site in one IC and the recording site in the other.…”

Section: Influence Of Commissural Input On Frequency Responses In the Ic V-shaped (A) And Nonv-shaped (B) Response Areas For Single Neuromentioning

confidence: 99%

Unifying the Midbrain

Rees

Orton

2018

The Oxford Handbook of the Auditory Brainstem

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Commissural fibres interconnecting the two sides of the brain are found at several points along the auditory pathway, thus suggesting their fundamental importance for the analysis of sound. This chapter presents an overview of what is currently known about the anatomy, physiology, and behavioral influences of the commissure of the inferior colliculus (CoIC)—the most prominent brainstem auditory commissure—that reciprocally interconnects the principal nuclei of the auditory midbrain, the inferior colliculi (IC). The primary contribution to the CoIC originates from neurons projecting from one inferior colliculus to the other, with the dorsal cortex and central nucleus providing the most extensive connections. In addition, many ascending and descending auditory centers send projections to the IC via the CoIC, together with diverse sources located outside the classically defined auditory pathway. The degree of interconnection between the two ICs suggests they function as a single entity. Recent in vivo evidence has established that CoIC projections modulate the neural representation of sound frequency, level, and location in the IC, thus indicating an important role for the CoIC in auditory processing. However, there is limited evidence for the influence of the CoIC on auditory behavior. This, together with the diversity of sources projecting via the CoIC, suggest unknown roles that warrant further exploration.

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Bilateral collicular interaction: Modulation of auditory signal processing in frequency domain

Cited by 12 publications

References 66 publications

Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice

Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice

Long-Term Impairment of Sound Processing in the Auditory Midbrain by Daily Short-Term Exposure to Moderate Noise

Unifying the Midbrain

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