longer. The patient in our case had used the CPAP face mask each night for 3 years.Based on a single patient case, we cannot conclude that CPAP is a primary cause of soft tissue chondromas. However, based on the etiology, it is possible that the CPAP face mask was the cause of the soft tissue chondroma on the chin in the present case. The chondroma was located at the mandible border where soft tissue padding is thinner than that at other areas where the mask touches the face. Although a CPAP mask might be well fitted, without leakage or pressure sores, the airway tube connected to the CPAP machine might place additional pressure on the mandible border. Cumulative irritation of the mandibular border several hours a night might induce soft tissue metaplasia and lead to the development of a chondroma. In cases where a lesion develops on the adhesive side of a CPAP mask, as in our patient, the lesion should be followed up by radiologic evaluation. Surgical treatment will likely be required in such cases. Changing a fullface CPAP mask to a nasal mask could prevent the formation of a soft tissue chondroma of the chin.We described a rare soft tissue chondroma of the chin. Considering the rare presentation on the facial region, the microtrauma of the mental region due to continuous use of the CPAP facial mask may play a role in the etiology.