Bilateral Corneal Dermoids

Henkind, Paul; Marinoff, Gerald P.; Manas, Alan; Friedman, Alan H.

doi:10.1016/0002-9394(73)90091-3

Cited by 39 publications

(20 citation statements)

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“…This tissue then develops into a tegument, with all the histological characteristics of normal skin [1][2][3]. Although dermoids affecting the eye and its adnexa are mostly unilateral, some authors have reported cases of bilateral disease [6,[12][13][14][15][16]21]. The hereditary nature of this affliction has been demonstrated in cats [8,9], cows [14], and horses [11], as well as humans [24].…”

Section: Discussionmentioning

confidence: 99%

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Canine Bilateral Conjunctivo-Palpebral Dermoid: Description of Two Clinical Cases and Discussion of the Relevance of the Terminology

Balland¹,

Raymond

Mathieson³

et al. 2015

Case Reports in Veterinary Medicine

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Two young dogs were presented for the evaluation of an abnormally haired appearance of both eyes since adoption. In one dog, the lesions were symmetrical and appeared as disorganized skin tissue located on the cutaneous aspect of the lateral portion of both lower eyelids, and continuing to the palpebral and the bulbar conjunctiva, thus forming continuous lesions. In the other dog, a similar lesion was present in the right eye (OD), but the lesion of the left eye (OS) was of discontinuous, disorganized skin tissue located midway on the lower eyelid and on the lateral bulbar conjunctiva. The lesions were surgically removed and routinely processed for histopathological analysis. Definitive diagnosis was conjunctivo-palpebral dermoids for each dog. Dermoids are usually considered to be choristoma (normal tissue in an abnormal location) when they are located on the ocular surface (cornea and/or conjunctiva) and as hamartoma when located on the palpebral skin. The lesion presentation in these two dogs reveals that names of "choristoma" alone or "hamartoma" alone are not accurate to depict the continuous, composite, conjunctivo-palpebral dermoids. These cases suggest that choristoma and hamartoma might develop subsequently from the same abnormal event during the embryonic development, which means that the lesion location might be the only difference between the two terms.

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Section: Discussionmentioning

confidence: 99%

“…Human ocular dermoids have also been described. They can be isolated lesions or a component of Goldenhar syndrome, which also affects other organs [21][22][23][24]. In dogs, the most frequent form is the conjunctivo-corneal dermoid [3].…”

Section: Introductionmentioning

confidence: 99%

Canine Bilateral Conjunctivo-Palpebral Dermoid: Description of Two Clinical Cases and Discussion of the Relevance of the Terminology

Balland¹,

Raymond

Mathieson³

et al. 2015

Case Reports in Veterinary Medicine

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“…1 Mann 2 classified corneal dermoids into three broad types. Our case belonged to grade II with corneal involvement sparing deep stroma, descemet's membrane, and endothelium.…”

Section: Commentmentioning

confidence: 99%

“…4 Corneal dermoids with no anterior chamber involvement require LK in which the lesion is excised to its entirety and a lamellar graft is tailored to fit the defect. 1 LK has the advantage of avoiding most postoperative complications associated with PK especially less risk of allograft rejection but has the major disadvantage of interface scarring and hazy graft. Of late, DLK is being performed more commonly over LK/PK with minimal reports of interface scarring.…”

Section: Commentmentioning

confidence: 99%