Bilateral Gynecomastia in a Preadolescent Boy While Under Treatment With Methylphenidate and Paroxetine

Coşkun, Murat; Adak, İbrahim; Akaltun, İsmail

doi:10.1097/jcp.0000000000000141

Cited by 10 publications

(7 citation statements)

References 16 publications

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“…Nausea, decreased appetite, weight loss, and sleep disturbances are among the most frequently reported side effects during MPH treatment (Green 2007). In addition to these common side effects, MPH has also been reported to cause some unusual side effects such as hallucinations (Coskun and Zoroglu 2008), hypersexuality or inappropriate sexual behaviors , skin eruptions ), manic/psychotic reactions (Ross 2006), obsessive-compulsive symptoms (Coskun 2011) and gynecomastia (Coskun et al 2014). These unusual side effects may cause treatment noncompliance, and may have important medical and/or mental health consequences.…”

Section: Discussionmentioning

confidence: 96%

Painful Muscle Cramps Possibly Associated with Withdrawal from Methylphenidate

Coşkun

Kaya

2016

Journal of Child and Adolescent Psychopharmacology

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Section: Discussionmentioning

confidence: 96%

Painful Muscle Cramps Possibly Associated with Withdrawal from Methylphenidate

Coşkun

Kaya

2016

Journal of Child and Adolescent Psychopharmacology

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“…Only a few reports of MPH-induced gynecomastia have appeared in the literature. Coşkun et al [6] reported gynecomastia during OROS MPH (Concerta) use in a boy of 10 [6]. Ensat et al [5] reported unilateral gynecomastia associated with MPH use in a six-year-old boy.…”

Section: Discussionmentioning

confidence: 99%

“…Ensat et al [5] reported unilateral gynecomastia associated with MPH use in a six-year-old boy. The case of Coşkun et al [6] used paroxetine and MPH therapy, and gynecomastia occurred six months after dosage increase. No regression in gynecomastia occurred after the drug discontinuation.…”

Section: Discussionmentioning

confidence: 99%

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Gynecomastia: A Rare Adverse Effect of Methylphenidate in an Adolescent Boy

Karayağmurlu

Varli

Coşkun

2020

Clin Psychopharmacol Neurosci

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Gynecomastia is a benign condition developing in association with localized fat deposition and glandular tissue proliferation in the breast in males, and characterized by breast growth. Drug is one of the most important factors in the etiology of gynecomastia. Methylphenidate is a commonly preferred and well-tolerated drug in the treatment of attention deficit hyperactivity disorder in children and adolescents. Gynecomastia is an uncommon side-effect of methylphenidate use. We report a case of bilateral gynecomastia developing in a dose-dependent manner during methylphenidate monotherapy and resolving with discontinuation of medication in a 15-year-old patient with a history of a similar side-effect during previous use of the drug. To the best of our knowledge this is one of the few case reports of gynecomastia developing in association with methylphenidate.

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“…Nausea, decreased appetite, weight loss, and sleep disturbances are among the most frequently reported adverse effects during MPH treatment (5). Besides these common adverse effects, MPH has also been reported to cause some unusual adverse effects such as hallucinations (6), hypersexuality or inappropriate sexual behaviors (7), skin eruptions (8,9), obsessive-compulsive symptoms (10), gynecomastia (11), and painful muscle cramps (12).…”

Section: Discussionmentioning

confidence: 99%

Erkek bir ergende metilfenidat ile indüklenen hiperhidrozis

Adak¹,

Kaya²,

Coşkun³

2017

Anadolu Kliniği Tıp Bilimleri Dergisi

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Hyperhidrosis (excessive sweating) is a rarely reported side effect of methylphenidate treatment in young subjects with attention-deficit/hyperactivity disorder. There are few reports of hyperhidrosis associated with methylphenidate overdose in children and adolescents with diagnosis of ADHD. Here we report a case of an adolescent boy who developed hyperhidrosis after taking osmotic-controlled release oral delivery system methylphenidate (Concerta®) for his attention-deficit/hyperactivity disorder. Keywords: Methylphenidate; hyperhidrosis; ADHD; adolescent Öz Hiperhidrozis (aşırı terleme) dikkat eksikliği ve hiperaktivite bozukluğu nedeniyle metilfenidat tedavisi uygulanan çocuklarda nadiren bildirilmiş bir ilaç yan etkisidir. Dikkat eksikliği ve hiperaktivite bozukluğu tanılı çocuk ve ergenlerde aşırı doz metilfenidat alımına bağlı hiperhidrozis bildirilen birkaç vaka örneği vardır. Bu yazımızda dikkat eksikliği ve hiperaktivite bozukluğunu tedavi için uzun etkili metilfenidat (Concerta®) kullanımı sonrasında hiperhidrozis yan etkisi gö-rülen bir hastayı sunmaktayız.

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Bilateral Gynecomastia in a Preadolescent Boy While Under Treatment With Methylphenidate and Paroxetine

Cited by 10 publications

References 16 publications

Painful Muscle Cramps Possibly Associated with Withdrawal from Methylphenidate

Painful Muscle Cramps Possibly Associated with Withdrawal from Methylphenidate

Gynecomastia: A Rare Adverse Effect of Methylphenidate in an Adolescent Boy

Erkek bir ergende metilfenidat ile indüklenen hiperhidrozis

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