Bilateral hearing loss after dichloromethane poisoning: A case report

Bonfiglioli, Roberta; Carnevali, Lucio; Lello, Matteo Di; Violante, Francesco Saverio

doi:10.1002/ajim.22257

Cited by 11 publications

(14 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The duration of low back pain was longer in clinical and the duration of absenteeism was longer among office staff, yet these differences were not significant. These results were similar to previous studies (14)(15)(16).…”

Section: Discussionsupporting

confidence: 93%

Chronic Low Back Pain Frequency and its Risk Factors in Clinical and Office Staff of Hospitals

Assadi

2015

Middle East J Rehabil Health

View full text Add to dashboard Cite

Background: Some occupations have risk factors for chronic low back pain; clinical staff of hospitals are good examples for encountering many risk factors yet office staff encounter a few or may be at risk of unknown factors for occupational low back pain. Objectives: The objective of this study was to compare chronic low back pain frequency and risk factors between clinical and office staff. Patients and Methods: A cross-sectional study on clinical and office staff at hospitals was done by completing a questionnaire with interviews and a checklist. Data were analyzed with the SPSS software version 16 using chi-2, T-test and regression with significance level of P < 0.05. Results: No significant difference was observed between the two groups in terms of chronic low back pain; frequency of low back pain in clinical staff was 18% (18 individuals) and in office staff this was 17% (17 individuals) (P < 0.05). Chronic low back pain in the clinical group might be related to flexion and extension, twisting, pulling or pushing, carrying, handling of patients, and sitting (P value < 0.001), and in office staff it might be related to flexion and extension, twisting and long durations of time spent driving (P value < 0.001). Conclusions: Frequency of low back pain was not significantly different between clinical and office staff. Chronic low back pain in clinical staff was related to work while in office staff it was related to some occupational and non-occupational risk factors.

show abstract

Section: Discussionsupporting

confidence: 93%

Chronic Low Back Pain Frequency and its Risk Factors in Clinical and Office Staff of Hospitals

Assadi

2015

Middle East J Rehabil Health

View full text Add to dashboard Cite

show abstract

“…Pryor [44] categorised both agents as non-ototoxic. Note that there is a report of a woman who developed bilateral hearing loss after overexposure to dichloromethane [45]. Thus, we hypothesise that the auditory signs observed in styrene-exposed subjects may not be exclusive to styrene exposure.…”

Section: Limitations Of the Study And Suggestions For Further Researchmentioning

confidence: 72%

Cochlear dysfunction is associated with styrene exposure in humans

2020

View full text Add to dashboard Cite

show abstract

“…Thirdly, the health effects of other chemical substances used in the laboratory where the patient worked, or potential secondary health effects generated while various chemicals were used in combination with organic solvents, were not evaluated. In addition, another drawback in this case report is that biological monitoring markers for dichloromethane such as blood levels of carboxyhemoglobin (COHb) or urinary dichloromethane [ 40 , 41 ] were not evaluated in the exposure assessment.…”

Section: Discussionmentioning

confidence: 99%

IgA nephropathy in a laboratory worker that progressed to end-stage renal disease: a case report

Min

Kim

Kang

et al. 2016

Ann of Occup and Environ Med

View full text Add to dashboard Cite

BackgroundIgA nephropathy (IgAN) is the most common form of glomerulonephritis, a principal cause of end-stage renal disease (ESRD) worldwide. The mechanisms of onset and progression of IgAN have not been fully revealed, and epidemiologic studies have yielded diverging opinions as to the role of occupational exposure to organic solvents in the initiation or worsening of IgAN. As the authors encountered a laboratory worker with IgAN that progressed to ESRD, we present a case report of IgAN progression due to dichloromethane exposure along with a review of literature.Case presentationA 41-year-old male laboratory worker began to experience gross painless hematuria after two years of occupational exposure to toluene. Although clinical follow-up was initiated under the impression of IgAN based on clinical findings, the patient continued to work for four more years in the same laboratory, during which he was in charge of laboratory analysis with direct exposure to a high concentration of dichloromethane without proper protective equipment. During that time, his renal function rapidly worsened and finally progressed to ESRD 10 years after the first clinical symptoms. The result of exposure assessment through reenactment of his work exceeded the occupational exposure limit for dichloromethane to a considerable degree.ConclusionsThe causal association between occupational solvent exposure and IgAN is still unclear; therefore, this case report could be used as a basis to support the relevance of occupational solvent exposure to IgAN and/or its progression. Early intervention as well as close monitoring of laboratory workers exposed to various organic solvents is important to prevent or delay the progression of glomerulonephritis to ESRD in the occupational setting.

show abstract

Bilateral hearing loss after dichloromethane poisoning: A case report

Cited by 11 publications

References 20 publications

Chronic Low Back Pain Frequency and its Risk Factors in Clinical and Office Staff of Hospitals

Chronic Low Back Pain Frequency and its Risk Factors in Clinical and Office Staff of Hospitals

Cochlear dysfunction is associated with styrene exposure in humans

IgA nephropathy in a laboratory worker that progressed to end-stage renal disease: a case report

Contact Info

Product

Resources

About