Bilateral hilar lymphadenopathy in a young female: a case report

Varma, Seema; Gupta, Shilpi; Elsoueidi, Raymond; Dhar, Meekoo; Talwar, Jotica; Mobarakai, Neville

doi:10.1186/1752-1947-1-60

Cited by 3 publications

(3 citation statements)

References 4 publications

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“…First, COP seldom presents with swollen hilar and mediastinal lymph nodes. The current literature showed that there were only two cases of patients with organizing pneumonia associated with hilar and mediastinal lymph nodes [14,15]. Second, most COP patients respond to glucocorticoid therapy well.…”

Section: Discussionmentioning

confidence: 99%

Organizing pneumonia secondary to lung cancer of unknown primary site

Mao

Zhang

Hou

et al. 2019

Respiratory Medicine Case Reports

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Background Secondary organizing pneumonia (OP) is associated with other pathological conditions, such as infections, drugs, cancers and radiotherapy. Lung cancer-associated secondary OP has rarely been reported. Case review In this study, we reported on a case of secondary OP caused by lung cancer. The patient was initially diagnosed with community-acquired pneumonia and then cryptogenic organizing pneumonia by CT scan-guided and transbronchial lung biopsy. Poor response to anti-infection or corticosteroid therapy prompted us to search for underlying disease. A TBNA biopsy of the 4R mediastinal lymph node revealed the diagnosis of lung cancer. Conclusion OP secondary to lung cancer of unknown primary site are rare. When OP patients have lymphadenopathy or poor response to glucocorticoid, a more differential diagnosis should be considered, especially for avoiding the misdiagnosis of a malignancy.

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Section: Discussionmentioning

confidence: 99%

Organizing pneumonia secondary to lung cancer of unknown primary site

Mao

Zhang

Hou

et al. 2019

Respiratory Medicine Case Reports

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“…A retrospective study conducted to determine prevalence of mediastinal lymphadenopathy in COP from University of British Columbia determined that COP may be associated with enlarged mediastinal lymph nodes but usually only one or two nodal stations are enlarged 8. Varma et al 9 reported the first case of COP presenting with bilateral hilar and mediastinal lymphadenopathy and our case is the second COP case.…”

Section: Discussionmentioning

confidence: 60%

Cryptogenic organising pneumonia presenting with bilateral hilar and mediastinal lymphadenopathy

et al. 2013

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Cryptogenic organising pneumonia is not considered in the differential diagnosis of bilateral hilar and mediastinal lymphadenopathy. We submitted a patient presenting with bilateral hilar and mediastinal lymphadenopathy. We suspected diagnosis of sarcoidosis, but the patient was diagnosed as cryptogenic organising pneumonia with the histological result. This is the second case report of cryptogenic organising pneumonia presenting with bilateral hilar and mediastinal lymphadenopathy.

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“…[ 12 ], mild mediastinal lymph node enlargement was present in ∼20% of the patients. To our knowledge, three previous cases of OP presenting with extensive lymphadenopathy have been reported in literature [ 13 – 15 ].…”

Section: Discussionmentioning

confidence: 99%

An unusual presentation of a more common disease entity

Kerkhove

Wever

Verbeken

et al. 2018

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A 66-year-old, male patient with a 10-pack-year history of smoking was referred to the internal medicine consultation because of a 4-week history of fatigue, weakness, intermittent low-grade fever, appetite and weight loss, and a mild dry cough. His previous history was unremarkable and his physical examination was normal. Routine laboratory screening revealed leukocytosis (11.08×109 leukocytes per L), elevated C-reactive protein (72.1 mg⋅L−1) and erythrocyte sedimentation rate 57 mm⋅h−1. Analyses for rheumatoid factor, antinuclear antibodies, and cytoplasmic and perinuclear anti-neutrophil cytoplasmic antibodies were all negative. Pulmonary function tests (static and dynamic volumes, flow–volume curve, and lung diffusion capacity) were within the predictive values. Chest radiography demonstrated bilateral hilar enlargement. The patient subsequently underwent a computed tomography (CT) scan of the chest (figure 1).

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Bilateral hilar lymphadenopathy in a young female: a case report

Cited by 3 publications

References 4 publications

Organizing pneumonia secondary to lung cancer of unknown primary site

Organizing pneumonia secondary to lung cancer of unknown primary site

Cryptogenic organising pneumonia presenting with bilateral hilar and mediastinal lymphadenopathy

An unusual presentation of a more common disease entity

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