Bilateral hypopyon in syphilitic uveitis

Collazo, Monica P. Gonzalez; Rodriguez, Nicole P. Rebollo; Santiago-Vázquez, Marely; Crespo-Ramos, Susanne M.; Marcos-Martínez, María J.; Villegas, Víctor M.; Oliver, Armando L.

doi:10.1016/j.ajoc.2020.101007

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…Nonetheless, HIV coinfection is common in patients with syphilis, stressing the importance of testing for HIV in patients with all types of syphilitic uveitis. 3 , 4,15 In our review, one patient’s being diagnosed with SOR later led to him also being diagnosed with HIV, while another patient with SOR had a concomitant HIV infection. 6,11…”

Section: Resultsmentioning

confidence: 86%

“…As with all patients with uveitis, individuals suspected of having AZOOR or an AZOOR complex–associated condition should be tested for syphilis. 3 -5 Such testing should be performed with a treponemal-specific test, such as the fluorescent treponemal antibody absorption test or the T pallidum passive particle agglutination assay; some patients with ocular manifestations of syphilis may have negative results from a rapid plasma reagin or Venerial Disease Research Laboratory test owing to their lower sensitivity. 3 Likewise, all patients with ocular syphilis should be tested for HIV, as the conditions share multiple risk factors and coinfection is common.…”

Section: Discussionmentioning

confidence: 99%

“…3 Likewise, all patients with ocular syphilis should be tested for HIV, as the conditions share multiple risk factors and coinfection is common. 3,4,15…”

Section: Discussionmentioning

confidence: 99%

“…3 Typically, posterior segment involvement may reveal distinctive preretinal yellowish aggregates, which are theorized to be treponemal bacterial and inflammatory precipitates. 4 However, syphilis may masquerade as other well-defined uveitides, such as multiple evanescent white-dot syndrome, Vogt-Koyanagi-Harada syndrome, or acute posterior multifocal placoid pigment epitheliopathy. 3,5…”

Section: Introductionmentioning

confidence: 99%

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Syphilitic Outer Retinopathy: A Case Report and Review of the Literature

Amaral

Joy

Jimenez

et al. 2021

Journal of VitreoRetinal Diseases

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Purpose: This work presents a case of syphilitic outer retinopathy with findings similar to those of acute zonal occult outer retinopathy (AZOOR). We also discuss the clinical characteristics, treatment, and prognosis of this entity. Methods: A case report and systematic literature review are presented. Results: A 56-year-old woman presented with acute vision loss, localized photopsia, a central scotoma, and retinal findings that were all consistent with AZOOR. A further workup led to a diagnosis of syphilis. Oral prednisone and intravenous penicillin resulted in the resolution of the posterior uveitis and the restoration of visual acuity. However, the central scotoma remained at the 3-year follow-up visit. Conclusions: Syphilitic outer retinopathy is a distinct entity characterized by the disruption of the ellipsoid zone visible on optical coherence tomography and a corresponding increase in fundus hyperautofluorescence in the affected areas. Although some patients may present with a demarcation line, as is seen with AZOOR, the fundus is oftentimes unremarkable or may show only subtle retinal pigment epithelium changes. Uveitis resolution and visual acuity restoration may be expected following treatment; however, visual field disturbances may persist.

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Section: Resultsmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

“…3 Likewise, all patients with ocular syphilis should be tested for HIV, as the conditions share multiple risk factors and coinfection is common. 3,4,15…”

Section: Discussionmentioning

confidence: 99%