Bilateral isolated adrenal coccidioidomycosis

Papadopoulos, Konstantinos I.; Castor, Birgitta; Klingspor, Lena; Dejmek, Annika; Lorén, Ingemar; Bramnert, Margareta

doi:10.1046/j.1365-2796.1996.407760000.x

Cited by 14 publications

(5 citation statements)

References 5 publications

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“…Isolated adrenal involvement has been reported in immunocompetent hosts with histoplasmosis, coccidioidomycosis, paracoccidioidomycosis, and pneumocystosis. [116][117][118][119] Much more often, the adrenal glands are involved in widely disseminated mycoses; at autopsy, histoplasmosis and paracoccidioidomycosis are by far the most common fungal infections found to have infiltrated the adrenal glands 9,34,45-49,92-95,98,120-123 (Table 2). Most such cases are asymptomatic, and antemortem diagnosis is rare.…”

Section: Mycosesmentioning

confidence: 99%

“…Adrenal reserve can also be affected by systemic mycoses, such as histoplasmosis, cryptococcosis, coccidioidomycosis, paracoccidioidomycosis, pneumocystosis, and blastomycosis. 93,[116][117][118]120,123 In particular, 50% of patients with paracoccidioidomycosis have diminished adrenal reserve, as evidenced by attenuated cortisol increments after corticotropin administration. 129 Such patients are asymptomatic, but fatal adrenal failure can occur in conditions of physiological stress.…”

Section: Mycosesmentioning

confidence: 99%

See 1 more Smart Citation

Endocrine and Metabolic Manifestations of Invasive Fungal Infections and Systemic Antifungal Treatment

Lionakis

Samonis

Kontoyiannis

2008

Mayo Clinic Proceedings

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Systemic fungal infections are increasingly reported in immunocompromised patients with hematological malignancies, recipients of bone marrow and solid organ allografts, and patients with AIDS. Mycoses may infiltrate endocrine organs and adversely affect their function or produce metabolic complications, such as hypopituitarism, hyperthyroidism or hypothyroidism, pancreatitis, hypoadrenalism, hypogonadism, hypernatremia or hyponatremia, and hypercalcemia. Antifungal agents used for prophylaxis and/or treatment of mycoses also have adverse endocrine and metabolic effects, including hypoadrenalism, hypogonadism, hypoglycemia, dyslipidemia, hypernatremia, hypocalcemia, hyperphosphatemia, hyperkalemia or hypokalemia, and hypomagnesemia. Herein, we review how mycoses and conventional systemic antifungal treatment can affect the endocrine system and cause metabolic abnormalities. If clinicians are equipped with better knowledge of the endocrine and metabolic complications of fungal infections and antifungal therapy, they can more readily recognize them and favorably affect outcome.

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Section: Mycosesmentioning

confidence: 99%

Section: Mycosesmentioning

confidence: 99%

Endocrine and Metabolic Manifestations of Invasive Fungal Infections and Systemic Antifungal Treatment

Lionakis

Samonis

Kontoyiannis

2008

Mayo Clinic Proceedings

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“…Extrapulmonary dissemination can spread to skin or subcutaneous tissue, meninges, skeleton, endocrine glands, eye, liver, kidneys, genital organs, prostate, and the peritoneal cavity. [7][8][9][10][11][12][13][14][15][16]…”

Section: Introductionmentioning

confidence: 99%

Disseminated Coccidioidomycosis to the Gallbladder

Grewal

Bajaj

Petersen

et al. 2020

Journal of Investigative Medicine High Impact Case Reports

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Coccidioidomycosis is an infection caused by inhalation of arthroconidia produced by dimorphic fungi in the genus Coccidioides. Forty percent of patients will develop an influenza-like illness with symptoms suggestive of a mild and self-limited respiratory infection; however, 5% of these individuals will develop extrapulmonary disseminated disease. An immunocompromised patient presented with right upper quadrant pain, ultrasound with pericholecystic fluid, in which a percutaneous cholecystostomy contained biliary fluid that grew the fungus Coccidioides immitis. Patient was initiated on intravenous amphotericin therapy and was followed closely with postoperative bile drainage with eventual laparoscopic cholecystectomy. We present a very rare case of disseminated coccidioidomycosis to the gallbladder.

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“…In the face and neck region, lesions to the eye 4 and thyroid 5 have been reported. Other atypical sites of dissemination to other regions of the body have included the adrenals, 6 liver, 7 peritoneal cavity, 8 male genitourinary tract, 9 and kidneys. 10 To our knowledge, this is the second documented report of coccidioidomycoses of the parotid.…”

Section: Introductionmentioning

confidence: 99%