Bilateral juvenile renal dysplasia in a Norwegian Forest Cat

Aresu, Luca; Zanatta, Rayssa Ferreira; Pregel, Paola; Caliari, D.; Tursi, Massimiliano; Valenza, F.; Tarducci, Alberto

doi:10.1016/j.jfms.2008.08.004

Cited by 17 publications

(20 citation statements)

References 14 publications

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“…In human medicine, RD is one of the principal causes of childhood end-stage renal failure. In veterinary medicine, it has been described in several species, including cattle (Dunham and others 1989, Simon and others 1999, Ohba and others 2001, Castro and others 2007, Maxie and Newman 2007, Aresu and others 2009, Philbey and others 2009). In Japanese Black cattle, RD shows autosomal recessive inheritance, caused by CLDN16 mutations (Hirano and others 2000, Ohba and others 2000, Hirano and others 2002).…”

mentioning

confidence: 99%

Renal dysplasia in grey Alpine breed cattle unrelated to CLDN16 mutations

et al. 2012

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mentioning

confidence: 99%

Renal dysplasia in grey Alpine breed cattle unrelated to CLDN16 mutations

et al. 2012

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“…Studies related to renal dysplasia in felines do not describe cartilaginous or osseous metaplasia in the urinary tract (ARESU et al, 2009;AZIZI et al, 2010), which highlights the importance of the alterations described here.…”

Section: Case Reportmentioning

confidence: 68%

“…These signs are observed in dysplastic kidneys of humans and domestic animals (CIANCIOLO; MOHR, 2015) but not in felines. There are reports of amyloidosis in Abyssinian felines, polycystic kidneys in Persians (CIANCIOLO; MOHR, 2015), infantile polycystic kidneys in Persian mestizos (LEES, 1996), unilateral renal dysplasia in non-breed felines (AZIZI et al, 2010), and juvenile bilateral renal dysplasia in Norwegian Forest cats (ARESU et al, 2009). …”

Section: Introductionmentioning

confidence: 99%

“…Renal dysplasia, rarely reported in cats (ARESU et al, 2009), is a structural disorganization resulting from abnormal differentiation and presence of abnormal structures in nephrogenesis of hereditary or acquired origin (PICUTT;LEWIS, 1987;LEES, 1996;OHARA et al, 2001;CIANCIOLO;MOHR, 2015). Usually, these abnormalities are congenital, but in felines, canines, and pigs with a nephrogenic zone active at birth, dysplasia can be caused by diseases in the neonatal period where tissue differentiation is complete (CIANCIOLO; MOHR, 2015).…”

Section: Introductionmentioning

confidence: 99%

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Urethral dysontogenic metaplasia in cat with bilateral renal dysplasia

Sapin

Silva

Scheid

et al. 2017

SCA

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This paper to describe a case of dysontogenic urethral metaplasia in a one month old mongrel feline who also had bilateral renal dysplasia. Dysontogenic metaplasia in cats are scarce and this change may be associated with renal dysplasia and/or lower urinary tract. The animal had history of abdominal enlargement since birth and dysuria, eliminating urine only dropwise. Due to the poor prognosis we opted for euthanasia. At necropsy was observed enlarged and distended bladder, reduced kidneys and dilated and tortuous ureters. The urethra was thickened, hard to cut, and histologically, was replacing the connective tissue, cartilage and endochondral ossification areas, which features dysontogenic metaplasia. Both kidneys presented primitive appearance featuring dysplasia. Dysontogenic metaplasia in urinary tract feline with renal dysplasia, has not been described. Key words: Congenital disease. Malformation. Nephropathy. ResumoEste trabalho tem como objetivo descrever um caso de metaplasia disontogênica uretral em um felino sem raça definida de um mês de idade, que também apresentava displasia renal bilateral. Dados sobre metaplasia disontogênica em felinos são escassos e a alteração pode estar associada a displasia renal e/ ou do trato urinário inferior. O animal apresentava histórico de aumento abdominal desde o nascimento e disúria, eliminando a urina apenas por gotejamento. Devido ao prognóstico desfavorável optou-se pela eutanásia. Na necropsia observou-se bexiga aumentada e dilatada, rins diminuídos e ureteres dilatados e tortuosos. A uretra apresentava-se espessada e firme ao corte, e histologicamente, havia substituição ao tecido conjuntivo, áreas de cartilagem e zonas de ossificação endocondral, o que caracteriza metaplasia disontogênica. Ambos os rins apresentavam aspecto primitivo caracterizando a displasia renal. A metaplasia disontogênica no trato urinário de felinos com displasia renal, não tem sido descrita. Palavras-chave: Doença congênita. Malformação. Nefropatia.

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“…Dysplasia arises as a result of abnormal differentiation of cells leading to disorganised development of the renal parenchyma. 24 Bilateral juvenile renal dysplasia has been reported in a 5-month-old intact male Norwegian Forest Cat that presented in chronic renal failure. 24 On ultrasound examination, both kidneys were mildly enlarged but otherwise unremarkable.…”

Section: Renal Agenesis Dysplasia and Hypoplasiamentioning

confidence: 99%

Feline abdominal ultrasonography: what’s normal? what’s abnormal? The kidneys and perinephric space

Griffin

2020

Journal of Feline Medicine and Surgery

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Practical relevance: Abdominal ultrasound plays a vital role in the diagnostic work-up of many cats presenting to general and specialist practitioners. Ultrasound examination of the kidneys and perinephric space can provide important information on several conditions including chronic renal disease, hydronephrosis and perinephric pseudocyst formation. Clinical challenges: Despite ultrasonography being a commonly used modality, many practitioners are not comfortable performing an ultrasound examination or interpreting the resulting images. Even for the experienced ultrasonographer, differentiating between incidental findings, such as a medullary rim sign, and pathological changes can be challenging. Aim: This review, part of an occasional series on feline abdominal ultrasonography, discusses ultrasonographic examination of the normal and diseased kidney and perinephric space. Aimed at general practitioners who wish to improve their knowledge of and confidence in feline abdominal ultrasound, this review is accompanied by highresolution images and videos available online as supplementary material. A subsequent article will address ultrasonography of the collecting system including the renal pelvis and urinary bladder. Equipment: Ultrasound facilities are readily available to most practitioners, although use of ultrasonography as a diagnostic tool is highly dependent on operator experience. Evidence base: Information provided in this article is drawn from the published literature and the author's own clinical experience.

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Bilateral juvenile renal dysplasia in a Norwegian Forest Cat

Cited by 17 publications

References 14 publications

Renal dysplasia in grey Alpine breed cattle unrelated to CLDN16 mutations

Renal dysplasia in grey Alpine breed cattle unrelated to CLDN16 mutations

Urethral dysontogenic metaplasia in cat with bilateral renal dysplasia

Feline abdominal ultrasonography: what’s normal? what’s abnormal? The kidneys and perinephric space

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