“…Despite these encouraging reports most surgeons remain very wary of photorefractive keratectomy in forme fruste or keratoconic corneas, together with the uncertainty of long-term stability, especially in the light of reports of keratectasia after PRK in normal, forme fruste and keratoconic corneas and patients with a family history of keratoconus. 9,10,18,19 Kasparova and Kasparov 20 introduced the novel concept of combined photorefractive keratectomy and phototherapeutic keratectomy (PTK) in keratoconus, the idea being that the photorefractive keratectomy part of the treatment could influence the anterior corneal layers and block the pathological process, stimulating regenerative processes and preventing progression of keratoconus. This was based on their theory that after excimer laser treatment, the ablated layers are replaced by a new fibrocellular membrane with increased solidity and rigidity, which may then act like a 'corset' to the cornea, preventing progression.…”