Bilateral methachronous testicular germ cell tumor and testicular microlithiasis in a child: Genetic analysis and insights. A case report

Boudaoud, N.; Loron, Gauthier; Pons, Marianne; Landais, Emilie; Kozal, S.; Doco‐Fenzy, Martine; Poli-Mérol, M.L.

doi:10.1016/j.ijscr.2017.09.035

Cited by 1 publication

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“…However, in the presence of risk factors, testicular micro lithiasis was associated with a substantially elevated risk of testicular germ cell tumor. 11 Because there is a strong association between testicular microlithiasis and primary testicular neoplasia in the pediatric population. 12 Known risk factors for testicular cancer include a family history of the disease, a previously diagnosed germ cell tumor, subfertility, undescended testis, and testicular microlithiasis, characterized by intratesticular calcification.…”

Section: Discussionmentioning

confidence: 99%

Bilateral testicular micro lithiasis in pediatrics secondary to testicular trauma

Lopez-Cruz¹,

Dias²,

Gómez³

et al. 2018

ICPJL

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Introduction: Testicular micro lithiasis is defined as the presence of five or more testicular microcalcifications in a single ultrasound image. The clinical meaning is still unknown. It has been associated with: cryptorchidism, testicular torsion, varicocele, gonadal dysgenesis or chromosomal disorders such as Klinefelter syndrome, Down syndrome, McCune-Albright syndrome and Peuzt-Jeghers syndrome, which may be associated with testicular deterioration and infertility. Clinical case: A male patient of 10years. I present testicular trauma at the age of 5years 2months. With peri testicular hematoma, peri testicular and scrotal hematoma drainage was performed without incident. Its evolution was adequate and it was withdrawn at 48 hours after surgery. Five years after the surgery, he refers to inguinoscrotal pain. Physical examination revealed: testicular atrophy and mild hydrocele. Bilateral testicular ultrasound was performed. With the following findings: testicular micro-lithiasis in the parenchyma of both testicles. Discussion: In 2010, a meta-analysis did not report a causal link between testicular micro lithiasis and cancer in the absence of additional risk factors. Conclusion: There is not enough evidence in the current literature to support any clinical surveillance regimen in patients with testicular micro lithiasis. Self-examination is the most important factor in the early detection of testicular malignancy. Keywords: testicular micro lithiasis, testicular cáncer, microlithiasis

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Section: Discussionmentioning

confidence: 99%