Bilateral Multifocal Choroiditis With Serous Retinal Detachment in a Patient With Brucella Infection: Case Report and Review of the Literature

Rabinowitz, Ruth

doi:10.1001/archopht.123.1.116

Cited by 23 publications

(10 citation statements)

References 6 publications

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“…According to Woods [29] and Rolando [30], the host-pathogen interaction of humans and Brucella species occurs through 2 mechanisms: direct invasion of the ocular tissue by the microorganism, producing septic emboli to the uveal tissue ( figure 1C-D, which shows the evidence of septic emboli in a patient with brucellar endocarditis and focal choroiditis); and formation of immunoglobulin and circulating immune complexes (figure 1H) [30,31]. Improvement in visual acuity with systemic steroids supports the concept that ocular manifestations of brucellosis have an immune component [32].…”

Section: Discussionmentioning

confidence: 75%

Ocular Manifestations Associated with Brucellosis: A 26‐Year Experience in Peru

et al. 2008

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Section: Discussionmentioning

confidence: 75%

Ocular Manifestations Associated with Brucellosis: A 26‐Year Experience in Peru

et al. 2008

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“…Conjunctival and fundus petechiae were reported by Wechsler and Gustafson[ 2 ] (1942) and Beebe and Meneely[ 3 ] (1949) in cases of Brucella endocarditis especially by abortus and melitensis. Rabinowitz[ 4 ] et al . published a case report with bilateral peripapillary serous retinal detachments in a case of brucellosis where they postulated low-virulence Brucella organisms in choroidal tissue.…”

Section: Discussionmentioning

confidence: 99%

Bilateral serous choroidal detachment in brucellosis and its management and outcome: Literature review and case report

Adusumilli

Krupa

Shetty

et al. 2020

Indian J Ophthalmol

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To report an unusual case of a 71-year-old livestock farmer with systemic brucellosis and ocular involvement. Examination showed vitreous haze with bilateral serous choroidal detachment. He was treated with topical antibiotics and corticosteroids, Tab rifampicin 600 mg and doxycycline 100 mg for 6 weeks with visual recovery and complete resolution of serous choroidal detachment in 2 weeks. This is the first case of bilateral serous choroidal detachment in a case of systemic brucellosis. Immune-mediated complex and direct microbial invasion of uveal tissue leading to serous choroidal detachment is the proposed pathogenesis that responds well to topical corticosteroids.

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“…In 1951, Pagliarani [9] published a study entitled "Contribution to the knowledge of ocular manifestations due to Brucella infection in man" in which he stated that "in these circumstances the diagnosis is less easily done and this fact makes us to believe that the incidence of ocular manifestations is more frequent than the perusal of the literature would suggest". Since then, numerous types of ocular involvement have been described, such as uveitis, dacryoadenitis, episcleritis, chronic iridoscleritis, nummular keratitis, cataract, glaucoma, multifocal choroiditis, exudative retinal detachment, maculopathy, endophthalmitis, and optic neuritis [2,6,[10][11][12][13][14] .…”

Section: Literature Reviewmentioning

confidence: 99%