Bilateral non-traumatic acetabular and femoral neck fractures due to pregnancy-associated osteoporosis

Aynacı, Osman; Kerimoğlu, Servet; Öztürk, Çağatay; Saraçoğlu, Metehan

doi:10.1007/s00402-007-0439-z

Cited by 53 publications

(61 citation statements)

References 18 publications

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“…Nevertheless, that bone marrow edema is still an indication of fragility in the affected femora, and prophylactic arthroplasties have been carried out in women in whom the fracture risk was considered to be high. In women who do not fracture, the MRI and DXA abnormalities typically resolve rapidly within several months to a year, leading to a 20 -40% increase in femoral neck BMD as the edema subsides (31,43,128,147,301,335,573,892). Whether that is a real increase in mineralization or removal of an artifact from bone marrow edema remains uncertain.…”

Section: Human Datamentioning

confidence: 99%

Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery

Kovacs

2016

Physiological Reviews

383

524

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During pregnancy and lactation, female physiology adapts to meet the added nutritional demands of fetuses and neonates. An average full-term fetus contains ϳ30 g calcium, 20 g phosphorus, and 0.8 g magnesium. About 80% of mineral is accreted during the third trimester; calcium transfers at 300-350 mg/day during the final 6 wk. The neonate requires 200 mg calcium daily from milk during the first 6 mo, and 120 mg calcium from milk during the second 6 mo (additional calcium comes from solid foods). Calcium transfers can be more than double and triple these values, respectively, in women who nurse twins and triplets. About 25% of dietary calcium is normally absorbed in healthy adults. Average maternal calcium intakes in American and Canadian women are insufficient to meet the fetal and neonatal calcium requirements if normal efficiency of intestinal calcium absorption is relied upon. However, several adaptations are invoked to meet the fetal and neonatal demands for mineral without requiring increased intakes by the mother. During pregnancy the efficiency of intestinal calcium absorption doubles, whereas during lactation the maternal skeleton is resorbed to provide calcium for milk. This review addresses our current knowledge regarding maternal adaptations in mineral and skeletal homeostasis that occur during pregnancy, lactation, and post-weaning recovery. Also considered are the impacts that these adaptations have on biochemical and hormonal parameters of mineral homeostasis, the consequences for long-term skeletal health, and the presentation and management of disorders of mineral and bone metabolism.

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Section: Human Datamentioning

confidence: 99%

Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery

Kovacs

2016

Physiological Reviews

383

524

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“…8 Only 6 cases of bilateral femoral neck fractures secondary to transient osteoporosis have been reported. [9][10][11][12][13][14] case report…”

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confidence: 99%

Bilateral Subcapital Femoral Neck Fractures Secondary to Transient Osteoporosis during Pregnancy: A Case Report

Emami

Abdollahpour

Kazemi

et al. 2012

J Orthop Surg (Hong Kong)

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Transient osteoporosis during pregnancy is a rare, self-limiting disease. We report on a 36-year-old woman who had bilateral subcapital femoral neck fractures during the 6th month of pregnancy. The diagnosis was made 4 days after delivery, because radiography was declined by the patient for fear of radiation. Fixation was not feasible owing to bone resorption, and 2-stage bipolar hemiarthroplasty was therefore performed. Magnetic resonance imaging is the best non-invasive investigative tool for pregnant women with hip pain. Early detection can prevent complications and resorting to major surgeries.

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“…В случае недостаточ-ного поступлении кальция с пищей происходит усиление процессов резорбции костной ткани будущей матери, что сказывается на снижении минеральной плотности костной ткани (МПК) у родильниц [7][8][9]. Эти изменения в ряде случаев могут приводить даже к патологическим перело-мам [10][11][12][13][14]. На рис.…”

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The contribution of polymorphism in VDR gene FОKI in the development of osteopenia in pregnancy

et al. 2017

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The study involved 89 postpartum women and 97 nonpregnant women aged 20 to 35 years. The results of a genetic test compared with the BMD. In parturients in the lumbar spine the highest IPC and the value of the Z-scores were in patients with genotype FF, and the lowest with the genotype ff. Patients with the heterozygous genotype were charac terized by intermediate values of the BMD and Z-scores in the lumbar spine. A similar results was observed in the proximal femur and the distal forearm. The results of the correlation analysis showed a moderate negative correlation between the ff genotype and the level of BMD in lumbar spine (r = –0,44; p < 0.05) and proximal femur (r = –0.37; p < 0.05).

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Bilateral non-traumatic acetabular and femoral neck fractures due to pregnancy-associated osteoporosis

Cited by 53 publications

References 18 publications

Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery

Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery

Bilateral Subcapital Femoral Neck Fractures Secondary to Transient Osteoporosis during Pregnancy: A Case Report

The contribution of polymorphism in VDR gene FОKI in the development of osteopenia in pregnancy

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