Bilateral perianal inflammatory verrucous porokeratosis (porokeratosis ptychotropica)

Genitogluteal Porokeratosis: 10 Years to Make the Diagnosis!

“…Whether related to chronic rubbing and scratching or to the dyskeratotic keratinocytes beneath the cornoid lamellae, this finding may constitute another potential misleading histological feature. 10,11,13 It is unlikely that the unusual clinical and histopathological features of GGP be attributed solely to superimposed lichenification and recurrent infections. Based on the limited data so far, this subset of porokeratosis seems to be more sporadic, to be more associated with diabetes mellitus, and to portend no significant malignant risk.…”

“…7,8 The risk of malignant degeneration may reach 24% in cases of late-onset, linear, and/or long-standing large lesions, and in older patients or those with a history of radiation exposure. 9 GGP encompasses all cases of PM involving the genital and/or gluteal regions including cases previously reported under ''porokeratosis ptychotropica'' [10][11][12][13][14] ; plaque-type porokeratosis of the buttocks or gluteal region; and vulvar, penile, and scrotal porokeratosis. So far, less than 40 cases of GGP have been reported in the literature.…”

“…So far, less than 40 cases of GGP have been reported in the literature. [1][2][3][4][5]8,[10][11][12][13][14][15][16][17][18][19][20][21][22] A review of these cases revealed common atypical features that may justify considering this entity as a distinct type of porokeratosis. The atypicality manifested at the level of the clinical presentation, clinical associations and course, and even histology.…”

Hypertrophic perianal porokeratosis in association with superficial actinic porokeratosis of the leg

“…Perianal porokeratosis is particularly uncommon and we are aware of only four reported cases. These have included typical annular lesions, 2 linear porokeratosis progressing to squamous cell carcinoma 3 and finally two cases of porokeratosis ptychotropica 4,5 . The term ‘porokeratosis ptychotropica’ was introduced by Lucker et al .…”

“…to describe a chronic, bilateral, psoriasiform eruption extending onto the buttocks in a young male 4 . More recently an almost identical eruption in a young male has been reported 5 . Ptychotropica refers to the eruption's predilection for the flexural skin.…”