Bilateral phaeochromocytoma during pregnancy

Systematic review of phaeochromocytoma in pregnancy

“…Particular care must be taken to consider the possibility of multiple lesions in this young patient group and therefore to confirm physiological catecholamine secretion after excision of the tumour(s). Failure to perform this may risk a further lesion coming to light subsequently, as occurred in two patients in the present review16, 59.…”

“…Eighteen of the 27 women underwent surgical excision of the phaeochromocytoma during pregnancy, two of whom subsequently suffered fetal death in utero . Two of the 18 women had an unrecognized additional phaeochromocytoma: one woman underwent bilateral adrenalectomy for bilateral phaeochromocytoma in the 23rd week of pregnancy, experienced intrauterine death of a singleton fetus 3 days after surgery and subsequently a third intrathoracic phaeochromocytoma was found59; another woman underwent right adrenalectomy during pregnancy but an additional left phaeochromocytoma was discovered postpartum on CT16. One woman underwent an elective termination in the first trimester58.…”

“…The remaining suitable reports contained 77 women with phaeochromocytoma during pregnancy, involving 78 fetuses. Data are summarized in Tables 1 and 2 , and are available in full as an electronic supplementary file ( Table S1 , supporting information)5, 11–70.…”