Bilateral platelet rich plasma injections with assisted techniques for temporomandibular joint disorders

Simşek, Muhammed Eren

doi:10.18621/eurj.2016.2.1.42

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…The improvement in mandibular movement in group (I) is in agreement with the results obtained by several authors (10,15,16,20,33,34,36) who reported an increase in the measurements of mandibular movements including maximal interincisal opening, lateral and protrusive movements in their studies after injection of PRP.…”

Section: Discussionsupporting

confidence: 91%

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The Clinical Efficiency of Platelet Rich Plasma in the Treatment of Temporomandibular Joint Disorders

Hassan¹,

Ali

Abdulla

2016

Alexandria Dental Journal

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INTRODUCTION: Temporomandibular joint dysfunction (TMD) is a clinically significant condition which can be a source of acute or chronic orofacial pain and dysfunction including limitation of mandibular movement. Platelet-rich plasma (PRP) is a blood product that allows in a simple, low cost, and minimally invasive way to obtain a concentration of many growth factors when activated. Many researchers proved PRP safety and efficacy in the management of musculo articular disorders. OBJECTIVES: to evaluate the efficiency of intra-articular PRP injection in comparison with conventional arthrocentesis in the treatment of TMD. MATERIALS AND METHODS: Twenty patients suffering from TMD were included in the study diagnosed according to The Research Diagnostic Criteria for Temporomandibular disorders (RDC/TMD) and divided into two groups as follow; ten patients underwent intra-articular injections of 2 ml PRP into the temporomandibular joint (TMJ) (study group) and the other ten patients were treated by the conventional arthrocentesis using Ringer's solution (control group). The patients were clinically evaluated preoperatively and postoperatively at the intervals of 1week, 3, and 6 months. RESULTS: The differences between the two groups in all the measured parameters were statistically insignificant throughout the postoperative period. But PRP group showed superior result than arthrocentesis group regarding pain and tenderness, and inferior result in clicking. CONCLUSIONS: PRP injection is a safe and effective method in the treatment of TMDs.

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Section: Discussionsupporting

confidence: 91%

“…The reduction in pain in group (II) is in agreement with the results obtained by several authors (24,25,35,36) who reported an improvement in the pain level post arthrocentesis in their studies by washing out of inflammatory mediators by arthrocentesis which had its effect in pain reduction and increasing range of movement.…”

Section: Discussionsupporting

confidence: 91%

The Clinical Efficiency of Platelet Rich Plasma in the Treatment of Temporomandibular Joint Disorders

Hassan¹,

Ali

Abdulla

2016

Alexandria Dental Journal

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Treatment of temporomandibular joint internal derangement using MESNA injection

Mosleh

2024

BMC Oral Health

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Introduction The development of temporomandibular disorders specifically emphasizes the biochemical changes occurring in the synovial fluid at different stages of temporomandibular joint disease. Research has indicated that inflammation may be a primary reason behind the pain and dysfunction in temporomandibular joint diseases. Since its clearance several years ago, MESNA (sodium 2-mercaptoethanesulfonate) has been used in various formulations as a mucolytic drug in the respiratory domain. It operates by disrupting the disulfide bonds present between polypeptide chains within mucus. MESNA exhibits minimal tissue distribution, with the material being swiftly and thoroughly eliminated via the kidneys. Objectives To assess the efficacy of injecting MESNA directly into the Temporomandibular Joint to treat internal derangement. Materials and methods A randomized clinical trial was conducted on sixty patients who exhibited non-responsiveness to conventional treatment and were diagnosed with TMJ anterior disc displacement with reduction. The patients were chosen from the outpatient clinic of the Oral and Maxillofacial Surgery Department at Tanta University Faculty of Dentistry. Two equal groups of patients were randomly assigned to each other. Group I (Mesna group) received intra-articular injection with MESNA solution. Group II (Standard group) received arthrocentesis with lactated ringer solution followed by injection of Hyaluronic Acid (HA). The data was gathered by functional examinations such as maximum interincisal opening (MIO) and clicking. A Visual Analogue Scale (VAS) assessed pain severity before and after treatments. Results Both MESNA and HA showed significant improvement up to six months of the follow-up compared to preoperative status, as evidenced by better mouth opening, lateral excursion, lower clicking, and reduced pain score in patients with TMDs. MESNA showed significant improvement during follow-up compared to HA. Conclusion Compared to HA, MESNA showed a more noticeable improvement during the follow-up period.

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Comparative study of the use of arthrocentesis and arthrocentesis in addition with platelet rich plasma in management of temporomandibular joint internal derangement

Nabil

Seleem

Hassan

2019

OMX

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Background: Disc derangement disorders of the TMJ are a group of intra-articular biomechanical disorders in which there is an abnormal relationship in the functional 'articular cartilaginous' condyle-disc complex. Platelet-rich plasma (PRP) is a blood product that allows in a simple, low cost, and minimally invasive way to obtain a concentration of many growth factors when activated. Aim: To compare the use of arthrocentesis alone and arthrocentesis in addition with platelet rich plasma in management of TMJ internal derangement. Materials and Methods: fourteen patients with DDwOR were included in the study diagnosed according to The Research Diagnostic Criteria for Temporomandibular disorders (RDC/TMD) and divided into two groups as follow; seven patients underwent intra-articular injections of 2 ml PRP after arthrocentesis (study group) and the other seven patients were treated by the conventional arthrocentesis using Ringer's solution (control group). The patients were clinically evaluated preoperatively and postoperatively at the intervals of 1 month and 6 months. Results: The differences between the two groups in all the measured parameters were statistically insignificant throughout the postoperative period. Conclusion: injection is a safe and effective method in the treatment of TMDs.

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Bilateral platelet rich plasma injections with assisted techniques for temporomandibular joint disorders

Cited by 4 publications

References 16 publications

The Clinical Efficiency of Platelet Rich Plasma in the Treatment of Temporomandibular Joint Disorders

The Clinical Efficiency of Platelet Rich Plasma in the Treatment of Temporomandibular Joint Disorders

Treatment of temporomandibular joint internal derangement using MESNA injection

Comparative study of the use of arthrocentesis and arthrocentesis in addition with platelet rich plasma in management of temporomandibular joint internal derangement

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