Bilateral Sudden Sensorineural Hearing Loss and Chronic Venous Cerebrospinal Insufficiency: A Case Report

Alpini, D.; Bavera, P; Berardino, Federica Di; Barozzi, S.; Cesarani, Antonio

doi:10.1258/phleb.2012.012009

Cited by 15 publications

(15 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3,4 As reported in the literature, MS patients demonstrate a higher prevalence of CCSVI (mean 71%, n ¼ 1336) upon ultrasound and venographic examination in comparison with normal controls and patients without MS (mean 7.1%, n ¼ 505). 5 Recently, other pathologies such as migraine 6 and sudden sensorineural hearing loss 7 have been associated with CCSVI.…”

Section: Introductionmentioning

confidence: 99%

Chronic cerebrospinal venous insufficiency in Ménière disease

Berardino

Alpini

Bavera³

et al. 2014

Phlebology

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Chronic cerebrospinal venous insufficiency in Ménière disease

Berardino

Alpini

Bavera³

et al. 2014

Phlebology

View full text Add to dashboard Cite

show abstract

“…Although the pathophysiology of SSHL remains controversial, some asymmetric anatomical conditions may be responsible for the unilateral involvement of SSHL. Since the intracranial venous system is often asymmetric and cochlear venous insufficiency has been considered to be one of the causes of SSHL, we chose to focus our study on patients with SSHL to verify whether asymmetries of the intracranial venous drainage could play a role in the etiopathogenesis of SSHL 2,3,14,15 .…”

Section: Discussionmentioning

confidence: 99%

Relationship between the drainage pattern of the dural venous sinuses and hearing recovery in patients with sudden sensorineural hearing loss

Park

Kim

Kang

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Although cochlear venous insufficiency has been considered to cause sudden sensorineural hearing loss (SSHL), there is insufficient clinical evidence to support this hypothesis. We sought to determine whether there is a correlation between draining patterns of the dural venous sinuses and the side of the affected ear in SSHL, as well as hearing recovery. The medical records of 109 patients diagnosed with unilateral SSHL were retrospectively reviewed. Magnetic resonance images and pure tone audiometry were performed in all patients. We measured the dominance of the inferior petrosal sinus (IPS) and transverse-sigmoid sinus (TS/SS) ipsilateral to the affected ear. Most patients were characterized by asymmetric venous drainage (IPS, 53.2%; TS/SS, 81.7%). The dominant side of the IPS or TS/SS was independent of the side of the affected ear for all patients in this study. However, in 35 patients with early recovery within 2 weeks, the dominant side of TS/SS was significantly associated with the side of the affected ear (p = 0.011). Moreover, the dominance of both the IPS and TS/SS influenced hearing outcomes at 3 months. Dominant TS/SS ipsilateral to the affected ear, particularly in the presence of ipsilateral hypoplastic IPS, is associated with a favorable hearing prognosis of SSHL. Sudden sensorineural hearing loss (SSHL) is frequently associated with idiopathic etiology. Several theories concerning causes of SSHL have been proposed, including viral infection and autoimmune disease. Disruption of cochlear blood flow has also been considered as one of the factors explaining the potential pathophysiology of SSHL 1. Studies using an animal model have provided evidence to support vascular impairment as a possible cause of SSHL, since it is not possible to directly measure or visualize small amounts of blood flow in the cochlea using current techniques in humans 1. Similar to retinal vein occlusions, impaired venous return from the cochlear circulation is suspected to cause inner ear disorders 2. However, there are fewer experiments investigating the effect of venous congestion produced in the cochlea, compared to the number of experiments involving occlusion of arteries to the cochlea 2,3. The inferior cochlear vein (ICV) is the main draining vein of the cochlea. The ICV runs within the canal of Cotugno proximal to the cochlear aqueduct. Considering the venous drainage of the cochlea into the dural sinus, anatomic variability of adjacent sinuses, including the inferior petrosal sinus (IPS), transverse-sigmoid sinuses (TS/SS), or the jugular bulb, may affect the venous drainage of the cochlea and the development of hearing impairment. This theory of venous congestion is supported by the fact that the dural sinuses frequently have asymmetric drainage in the normal population. Prior studies have demonstrated that 23-35% and 72% of cases presented asymmetric structure of the IPS and TS/SS, respectively 4. In addition, there have been radiological studies showing significant asymmetry of the jugular bulb 5. Contrast-enhance...

show abstract

“…[1][2][3][4][5][6] His Patients and Friends all loved him for his patience and presence, together with a wonderful temper and a friendly word for all. Those who knew him well also appreciated his capacity for intuitions and ideas.…”

Section: Dario Alpini a Pioneer Of Venous And Lymphatics Disorders Omentioning

confidence: 97%