Bilateral thalamic stroke transiently reduces arousals and NREM sleep instability

Luigetti, Marco; Lazzaro, Vincenzo Di; Broccolini, Aldobrando; Vollono, Catello; Dittoni, Serena; Frisullo, Giovanni; Pilato, Fabio; Profice, Paolo; Losurdo, Anna; Morosetti, Roberta; Testani, Elisa; Colicchio, Salvatore; Marca, Giacomo Della

doi:10.1016/j.jns.2010.10.015

Cited by 34 publications

(11 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, acute lesions in the central nervous system after stroke might result in circadian phase shifts. Changes in sleep homeostasis with prolonged sleep latencies, fragmented sleep pattern, and disturbed NREM sleep were shown in human stroke patients ( 10 , 11 ) and discussed in the context of reduced subjective quality of life ( 29 ). Here, we did not find significant changes in sleep latency in our participants.…”

Section: Discussionmentioning

confidence: 99%

“…Several animal studies demonstrated that cerebrovascular events, in turn, also impact circadian rhythms and sleep architecture ( 6 – 9 ). Longer latencies to fall asleep, fragmented sleep, NREM sleep instability, and hypersomnia have also been described in stroke patients, indicating changes in sleep homeostasis and circadian rhythmicity after stroke ( 10 , 11 ). Two studies with small sample sizes provided some evidence of altered timing in urinary melatonin as a marker of disturbed circadian rhythms in stroke patients ( 12 , 13 ).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Changes in Chronotype after Stroke: A Pilot Study

et al. 2015

View full text Add to dashboard Cite

This study aimed to elucidate associations between stroke onset and severity as well as chronotype (phase of entrainment) and internal time of stroke. Fifty-six first-ever ischemic stroke patients participated in a cross-sectional study assessing chronotype (mid-sleep on work-free days corrected for sleep deficit on workdays; MSFsc) by applying the Munich ChronoType Questionnaire (MCTQ). The MCTQ was completed twice, on average 68 ± 24 (SD) days post stroke and retrospectively for the time before stroke. To assess the impact of stroke in relation to internal time, InTstroke was calculated as MSFsc minus local time of stroke. Stroke severity was assessed via the standard clinical National Institute Health Stroke Scale (NIHSS) and modified Ranking Scale (mRS), both at hospital admission and discharge. Overall, most strokes occurred between noon and midnight. There was no significant association between MSFsc and stroke onset. MSFsc changed significantly after stroke, especially in patients with more severe strokes. Changes in MSFsc varied with InTstroke – the earlier the internal time of a stroke relative to MSFsc-before-stroke, the more MSFsc advanced after stroke. In addition, we provide first evidence that MSFsc changes varied between stroke locations. Larger trials are needed to confirm these findings.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Changes in Chronotype after Stroke: A Pilot Study

et al. 2015

View full text Add to dashboard Cite

show abstract

“…TST, SE, S31S4, REM, and RL decreased significantly, and S1, SL, and WASO increased markedly in the cerebral infarction group (P , .05); however, there still exist some opposite views. 21,22 These results may be related to experimental surroundings, physical condition, mood, and so forth.…”

Section: Chen Et Almentioning

confidence: 93%

Research of Sleep Disorders in Patients with Acute Cerebral Infarction

Chen

Zhang

et al. 2015

Journal of Stroke and Cerebrovascular Diseases

View full text Add to dashboard Cite

“…Typical long-term conditions include amnesia62 63 65–67 and apathy 62 64 65 68. Other less frequent symptoms of bilateral paramedian thalamic infarctions that have been reported include recurrent episodes of paroxysmal sleep and unresponsiveness,69 70 hypersexuality,71 akinetic mutism72 and eyelid apraxia 73. The symptoms of ‘top of the basilar artery’ syndrome include unusual levels of alertness, sleep-wake cycle, behavior and oculomotor or pupillomotor functions 7.…”

Section: Clinical Differencesmentioning

confidence: 99%

Current differential diagnoses and treatment options of vascular occlusions presenting as bilateral thalamic infarcts: a review of the literature

Agarwal

Tolia

Hansberry

et al. 2012

J NeuroIntervent Surg

View full text Add to dashboard Cite

bilateral thalamic infarctions are rare and usually caused by vascular occlusions. When symptomatic, it is important to make a distinction between different vascular etiologies in order to provide an effective and timely therapeutic response. Clinical presentations may not adequately differentiate between the vascular etiologies alone. It is therefore important to use imaging technologies to distinguish appropriately the origin of the infarct so that proper treatment can be administered. Advanced imaging techniques, such as CT angiography and MR angiography, have proved useful for distinguishing between arterial and venous causes of bithalamic infarctions. Bilateral thalamic venous infarctions can be treated with anticoagulation medication and with thrombolysis in more severe cases. Bilateral thalamic arterial infarctions may be treated with thrombolysis.

show abstract

Bilateral thalamic stroke transiently reduces arousals and NREM sleep instability

Cited by 34 publications

References 15 publications

Changes in Chronotype after Stroke: A Pilot Study

Changes in Chronotype after Stroke: A Pilot Study

Research of Sleep Disorders in Patients with Acute Cerebral Infarction

Current differential diagnoses and treatment options of vascular occlusions presenting as bilateral thalamic infarcts: a review of the literature

Contact Info

Product

Resources

About