Bilateral tuberculous dacryoadenitis

Ayari, Rabie; Amri, R.; Chalbi, Emna; Sbai, Mohamed Ali

doi:10.4103/ijmy.ijmy_57_20

Cited by 2 publications

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“…According to Tang et al, among 97 patients, the most prevalent specific diagnoses were lymphoma, lymphoid hyperplasia, sarcoidosis, IOID, and lacrimal gland prolapse [ 1 ]. Other publications on bilateral lacrimal gland lesions are mostly case reports showing associations with Kimura’s disease [ 4 – 6 ], lacrimal gland agenesis [ 7 , 8 ], diffuse large B-cell lymphoma [ 9 ], COVID-19 dacryoadenitis [ 10 ], tuberculous dacryoadenitis [ 11 ], amyloidosis [ 12 ], Rosai-Dorfman disease [ 1 , 13 ], Still’s disease [ 14 ], TED [ 15 ], acute lymphocytic leukemia [ 16 ], sickle cell disease [ 17 ], and myeloproliferative diseases [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

Clinicopathologic features and outcomes of bilateral lacrimal gland lesions

He,

2024

PLoS ONE

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Background The present study reviewed the clinicopathological features and outcomes of bilateral lacrimal gland lesions. Methods The data of 113 patients who underwent lacrimal gland biopsy at the West China Hospital of Sichuan University, China, between January 1, 2010, and December 31, 2021, are presented in this case series. The patients all presented with bilateral lacrimal gland lesions. The collected data included patient demographics, clinical features, the results of laboratory examinations, imaging presentations, histopathological diagnoses, treatments, and outcomes. Results The mean age of the 113 enrolled patients was 47.4 ± 14.9 years (range, 11–77 years) with a predominance of females (54.9%, n = 62). The lacrimal gland was the source of the majority of biopsy tissue (98.2%, n = 111). The most prevalent etiology was immunoglobulin G4-related ophthalmic disease (IgG4-ROD) (32.7%, n = 37), followed by idiopathic orbital inflammation (IOI) (28.3%, n = 32), mucosa-associated lymphoid tissue (MALT) lymphoma (17.7%, n = 20), reactive lymphoid hyperplasia (RLH) (10.6%, n = 12), and mantle cell lymphoma (4.4%, n = 5). Patients with IOI were significantly younger than those with IgG4-ROD and MALT lymphoma (t = 2.932, P = 0.005; t = 3.865, P<0.001, respectively). Systemic symptoms were more prevalent among patients with IgG4-ROD (χ2 = 7.916, P = 0.005). The majority of patients were treated with surgery (53.1%, n = 60), with surgery combined with corticosteroid therapy (21.2%, n = 24) being the second most common treatment. The majority of patients (91.2%, n = 103) attained complete resolution, stable disease, or significant improvement. Conclusion In conclusion, there are several aetiologies associated with bilateral lacrimal gland lesions, the most prevalent being IgG4-ROD, IOI, and MALT lymphoma. Systemic symptoms were more common in patients with IgG4-ROD. The majority of patients who presented with bilateral lesions of the lacrimal glands responded satisfactorily to treatment, with favorable results.

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Section: Discussionmentioning

confidence: 99%

Clinicopathologic features and outcomes of bilateral lacrimal gland lesions

He,

2024

PLoS ONE

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A case of tuberculous dacryoadenitis with review of literature

Lahane

Munde

Chalvadi

et al. 2022

Indian Journal of Ophthalmology - Case Reports

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Lacrimal gland inflammation is commonly due to viral infection, autoimmune, and idiopathic inflammatory disease. Orbital and adnexal tuberculosis (OTB) is a rare entity even in the TB endemic country of India. TB dacryoadenitis is one of the presentations in the OTB spectrum, with less than 25 cases in the literature. We report the case of a 14-year-old female primarily presented with unilateral dacryoadenitis and cold abscess at the lower lumbar region. Biopsy of lacrimal gland confirmed on histopathology as tuberculosis. Systemic investigation revealed pulmonary and extrapulmonary TB. She was treated with systemic category I anti-tubercular treatment resulting in complete regression of disease.

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Bilateral tuberculous dacryoadenitis

Cited by 2 publications

References 2 publications

Clinicopathologic features and outcomes of bilateral lacrimal gland lesions

Clinicopathologic features and outcomes of bilateral lacrimal gland lesions

A case of tuberculous dacryoadenitis with review of literature

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