“…Although it has been studied mainly in primary hyperhidrosis, it has also been used in Raynaud's syndrome, facial flushing, and abdominal pain due to chronic pancreatitis, reflex sympathetic dystrophy or anginal syndromes. For Raynaud's syndrome, the scarce published literature defends its use as a last resort for refractory cases [1], offering an effective and safe treatment with favorable cosmetic results, reduced hospitalization and minimal postoperative pain. Sympathetic denervation causes long-term effects on lung function, cardiac function, skin coloration, and psychological status.…”