Corn flour has been stored at different moisture content (without and with 10 % water) and temperatures (-20, 4 and 25 °C). A modified quick, easy, cheap, effective, rugged and safe (QuEChERS) method was applied to determine the degradation rate of five common pesticides (imidacloprid, carbendazim, triadimefon, acetochlor and metolachlor) during the stored process using high-performance liquid chromatography with a diode array detector and gas chromatography with an electron capture detector. The results showed that there was almost no degradation on five pesticides at-20 °C in corn flour whether with or without water, and the half-life was 69.3-693.2 days. The degradation rate ranged from 1.7 to 7.8 % after ten days of application. Under 25 °C and 10 % moisture content, the half-life was sharply reduced to 5.8-14.4 days. Under this condition, the degradation rate ranged from 40.6 to 68.4 % after ten days of application, and the sequence from high to low of the five pesticides. The degradation rates were as follows: carbendazim, imidacloprid, acetochlor, metolachlor and triadimefon. Therefore, low temperature and drying were beneficial to the storage of corn flour, but unfavorable to the degradation of pesticides in corn flour.