Bildung von Dicarbonsäuren durchCandida guillier mondii, Stamm H 17, ausn-Alkanen

Krauel, H. H.; Kunze, Reinhard; Weide, H.

doi:10.1002/jobm.3630130105

Cited by 8 publications

(3 citation statements)

References 10 publications

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“…Our observation was similar to the results obtained by Krauel et al (1973), who found that glutaric acid and pimelic acid were produced predominantly in Candida guilliermondi grown on odd-carbon n-alkane such as C11 , C13 , C15 , C17 , and by Ogino et al (1965) from…”

Section: Discussionsupporting

confidence: 92%

Oxidation of n-alkanes by citric acid producingCandida spp.

Souw

Luftmann

Rehm

1977

European J. Appl Microbiol.

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Section: Discussionsupporting

confidence: 92%

Oxidation of n-alkanes by citric acid producingCandida spp.

Souw

Luftmann

Rehm

1977

European J. Appl Microbiol.

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“…as well as for the yeasts Candida guilliermondii and Candida spp. (Coon [ 2005 ]; Kester and Foster [ 1963 ]; Krauel et al [ 1973 ]; Watkinson and Morgan [ 1991 ]). At least some of the intermediates of the β-oxidation of this dicarboxylic acid were detected in the cultures of all investigated yeasts.…”

Section: Discussionmentioning

confidence: 99%

“…For diterminal degradation primary alcohols from the monoterminal pathway are hydroxylated at their ω-position resulting in the formation of diols. These are subsequently oxidized to ω-hydroxy fatty acids and then to dicarboxylic acids which are degraded by β-oxidation (Coon [ 2005 ]; Kester and Foster [ 1963 ]; Krauel et al [ 1973 ]; Watkinson and Morgan [ 1991 ]). For some bacteria and filamentous fungi also a subterminal degradation is possible.…”

Section: Introductionmentioning

confidence: 99%

Metabolism of alkenes and ketones by Candida maltosa and related yeasts

et al. 2014

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Knowledge is scarce about the degradation of ketones in yeasts. For bacteria a subterminal degradation of alkanes to ketones and their further metabolization has been described which always involved Baeyer-Villiger monooxygenases (BVMOs). In addition, the question has to be clarified whether alkenes are converted to ketones, in particular for the oil degrading yeast Candida maltosa little is known. In this study we show the degradation of the aliphatic ketone dodecane-2-one by Candida maltosa and the related yeasts Candida tropicalis, Candida catenulata and Candida albicans as well as Trichosporon asahii and Yarrowia lipolytica. One pathway is initiated by the formation of decyl acetate, resulting from a Baeyer-Villiger-oxidation of this ketone. Beyond this, an initial reduction to dodecane-2-ol by a keto reductase was clearly shown. In addition, two different ways to metabolize dodec-1-ene were proposed. One involved the formation of dodecane-2-one and the other one a conversion leading to carboxylic and dicarboxylic acids. Furthermore the induction of ketone degrading enzymes by dodecane-2-one and dodec-1-ene was shown. Interestingly, with dodecane no subterminal degradation products were detected and it did not induce any enzymes to convert dodecane-2-one.

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Isocitratlyase von Candida guilliermondii, Stamm H17. III. Regelung durch Intermediate des Alkanabbaus und allgemeines Regulationsmodell

Hildebrandt

Weide

1974

J of Basic Microbiology

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Isocitratlyase von Candida guillier rnondii, Stamm H 17 111. Regelung durch Intermediate des Alkanabbaus und allgemeines Regulationsmodell W. HILDEBRANDT und H. WEIDE (Eingegangen am 6 . 6 . 1 9 7 3 ) Die Aktivitat der Isocitratlyase wurde durch Capronsaure ( K I = 4,l mni) stark gehemmt,. Die anderen Monocarbonsauren mit geradzahligen C-Kettenlangen von 12 bis 2 sowie Adipinsaure und Hexanol beeinflufiten das Enzym nur schwach oder bewirkten keine Inhibition. Unter Berucksichtigung aller fur diese Hefe ermittelten Hemmwerte und -typen wurde ein Modell der Regelung der Isocitratlyase entwickelt.

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Bildung von Dicarbonsäuren durchCandida guillier mondii, Stamm H 17, ausn-Alkanen

Cited by 8 publications

References 10 publications

Oxidation of n-alkanes by citric acid producingCandida spp.

Oxidation of n-alkanes by citric acid producingCandida spp.

Metabolism of alkenes and ketones by Candida maltosa and related yeasts

Isocitratlyase von Candida guilliermondii, Stamm H17. III. Regelung durch Intermediate des Alkanabbaus und allgemeines Regulationsmodell

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