1968
DOI: 10.1016/s0140-6736(68)92888-2
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Bile-Salt Deconjugation and Steatorrhœa in Patients With the Stagnant-Loop Syndrome

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Cited by 172 publications
(47 citation statements)
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“…In healthy subjects the numbers and variety of organisms recovered from all levels of the bowel were greater than those reported by some previous workers (Shiner, Waters and Gray, 1963;Tabaqchali et al, 1966) but similar to those reported by others (Gorbach et al, 1967;Gorbach et al, 1969). Much less information is available about the microflora of the mid-gut and terminal ileum than of the upper small bowel.…”
Section: Discussionsupporting
confidence: 79%
“…In healthy subjects the numbers and variety of organisms recovered from all levels of the bowel were greater than those reported by some previous workers (Shiner, Waters and Gray, 1963;Tabaqchali et al, 1966) but similar to those reported by others (Gorbach et al, 1967;Gorbach et al, 1969). Much less information is available about the microflora of the mid-gut and terminal ileum than of the upper small bowel.…”
Section: Discussionsupporting
confidence: 79%
“…In normal anatomy, BAs in the upper intestine are dominated by primary conjugated BAs [34]. One possible explanation for the rise in unconjugated BAs could be that microbial contamination of the small intestine due to altered gut anatomy causes bacterial deconjugation of BAs and subsequently absorption in the biliopancreatic limb [34][35][36].…”
Section: Discussionmentioning
confidence: 99%
“…Additional models have been discussed by Ho and Higuchi (37) (43) and are increased in amount in disease (44). Passive diffusion could provide an effective alternative route of absorption for unconjugated acids.…”
Section: Net Water Movementmentioning
confidence: 99%