Biliary ascariasis in the etiology of recurrent pyogenic cholangitis in an endemic area

Khuroo, Mohammad Sultan; Khuroo, Naira Sultan; Khuroo, Mehnaaz S.

doi:10.5348/ijhpd-2015-30-oa-5

Cited by 7 publications

(8 citation statements)

References 25 publications

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“…81 Hospital-based studies in India have found that Ascaris may be the cause of approximately half of cases with biliary disease, a third of pancreatitis cases, and around 15% of liver abscesses and biliary lithiasis. [82][83][84] Clinicians in endemic areas must have a high suspicion of Ascaris infection, as cases may present as surgical emergencies.…”

Section: Clinical Presentationmentioning

confidence: 99%

Soil-transmitted helminth infections

et al. 2018

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More than a quarter of the world's population is at risk of infection with the soil-transmitted helminths Ascaris lumbricoides, hookworm (Ancylostoma duodenale and Necator americanus), Trichuris trichiura, and Strongyloides stercoralis. Infected children and adults present with a range of medical and surgical conditions, and clinicians should consider the possibility of infection in individuals living in, or returning from, endemic regions. Although safe and effective drugs are donated free to endemic countries, only half of at-risk children received treatment in 2016. This Seminar describes the epidemiology, lifecycles, pathophysiology, clinical diagnosis, management, and public health control of soil-transmitted helminths. Previous work has questioned the effect of population-level deworming; however, it remains beyond doubt that treatment reduces the severe consequences of soil-transmitted helminthiasis. We highlight the need for refined diagnostic tools and effective control options to scale up public health interventions and improve clinical detection and management of these infections.

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Section: Clinical Presentationmentioning

confidence: 99%

Soil-transmitted helminth infections

et al. 2018

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“…On repeated invasion, worms often cannot come out of the ductal lumen and die. Subsequent to worm death, sludge and stones form within the bile and hepatic ducts and evolves in to clinical entity of recurrent pyogenic cholangitis[ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Hepatobiliary and pancreatic ascariasis

Khuroo

Rather

Khuroo

et al. 2016

WJG

114

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Hepatobiliary and pancreatic ascariasis (HPA) was described as a clinical entity from Kashmir, India in 1985. HPA is caused by invasion and migration of nematode, Ascaris lumbricoides , in to the biliary tract and pancreatic duct. Patients present with biliary colic, cholangitis, cholecystitis, hepatic abscesses and acute pancreatitis. Ascarides traverse the ducts repeatedly, get trapped and die, leading to formation of hepatolithiasis. HPA is ubiquitous in endemic regions and in Kashmir, one such region, HPA is the etiological factor for 36.7%, 23%, 14.5% and 12.5% of all biliary diseases, acute pancreatitis, liver abscesses and biliary lithiasis respectively. Ultrasonography is an excellent diagnostic tool in visualizing worms in gut lumen and ductal system. The rational treatment for HPA is to give appropriate treatment for clinical syndromes along with effective anthelmintic therapy. Endotherapy in HPA is indicated if patients continue to have symptoms on medical therapy or when worms do not move out of ductal lumen by 3 wk or die within the ducts. The worms can be removed from the ductal system in most of the patients and such patients get regression of symptoms of hepatobiliary and pancreatic disease.

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“…The formation of stones is thought to result from the action of bacterial beta-glucuronidase on conjugated bilirubin. 1 Although the exact incidence in India is not known, the disease is quite common in Kashmir 2,3 and eastern parts of India.…”

Section: Introductionmentioning

confidence: 99%

“…2,[8][9][10][11][12] The aim of this article was to report the short and long-term outcomes of surgery for RPC from a tertiary center from Eastern India.…”

Section: Introductionmentioning

confidence: 99%