Biliary parasitic diseases including clonorchiasis, opisthorchiasis and fascioliasis

Lim, Jae Hoon; Mairiang, Eimorn; Ahn, Geung Hwan

doi:10.1007/s00261-008-9373-y

Cited by 22 publications

(48 citation statements)

References 28 publications

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“…This outcome is consistent with the previous studies finding that during the early infection phase, immature worms dig through liver parenchyma forming minute cavities, which mainly come from tissue necrosis, unlike a pyogenic abscess where a single large cavity is observed. 9,20 Histopathology of biopsies revealed necrosis with eosinophilic infiltrations. Thus, imaging could be quite useful for screening and suspecting cases in nonendemic regions.…”

Section: Discussionmentioning

confidence: 99%

“…Computed tomography (CT) can detect microabscesses caused by worms tunneling liver tissues, which is important in follow-up. 6,9 The drug of choice is triclabendazole at a single dose of 10 mg/kg body weight for for 2 days. 10 The clinical presentation of human fascioliasis infection is unusual, ranging from asymptomatic cases to cholangitis, hepatitis, and hepatic focal lesions (HFLs).…”

Section: Introductionmentioning

confidence: 99%

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Human Fascioliasis: A Re-emerging Disease in Upper Egypt

Mekky¹,

Tolba²,

Abdelmalek³

et al. 2015

The American Society of Tropical Medicine and Hygiene

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Abstract. In recent years, the number of humans infected with Fasciola has risen rapidly. Diagnosis is based mainly on detection of eggs in stool analysis. The rate of infection in Egypt is unknown. In this retrospective study, we describe 23 cases of hepatic fascioliasis, and only 2 of these cases showed eggs in stools. The symptoms of infection, such as pyrexia of unknown origin, epigastric pain, and abdominal distension, were suggestive. Imaging techniques, including abdominal ultrasonography and computed tomography, were very helpful in detecting hepatic changes. An indirect hemagglutination assay proved to be of value for diagnosis. Treatment using a 2-day triclabendazole regimen cured the infection and signs of hepatic involvement disappeared. Combining both imaging techniques and laboratory tests is essential for diagnosis of fascioliasis in the early stage.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Human Fascioliasis: A Re-emerging Disease in Upper Egypt

Mekky¹,

Tolba²,

Abdelmalek³

et al. 2015

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…Similar abnormal laboratory and radiological findings may represent viral hepatitis, liver abscess, malignancy, cholecystitis, sclerosing cholangitis, AIDS-related cholangitis, ruptured hydatid cyst, and parasites such as ascariasis and clonorchiasis (1,3). The specificity of the IHA method using purified adult F. hepatica antigen F1 for serological diagnosis of F. hepatica is 96.9% (18).…”

Section: Discussionmentioning

confidence: 99%

“…Diagnosis may be delayed because of the wide spectrum of the differential diagnosis and low incidence of F. hepatica infection (7). Similar abnormal laboratory and radiological findings may represent viral hepatitis, liver abscess, malignancy, cholecystitis, sclerosing cholangitis, acquired immunodeficiency syndrome (AIDS)-related cholangitis, ruptured hydatid cyst, and parasites such as ascariasis and clonorchiasis (1,3,4).…”

Section: Introductionmentioning

confidence: 99%