Biliary Reconstruction

Rossi, Ricardo L.; Tsao, Jane I.

doi:10.1016/s0039-6109(16)46383-8

Cited by 44 publications

(30 citation statements)

References 18 publications

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“…Carroll et al [16] reported a series of 46 BDIs with 16 IOCs of which 11 were interpreted incorrectly, and Thomson et al [19] reported 27 BDIs where 8 of the 10 IOCs were misinterpreted. Moreover, BDI may even originate at IOC by catheter manipulation [19,20]. Furthermore, IOC does not show the lesions induced after cholangiography.…”

Section: Discussionmentioning

confidence: 99%

Bile duct injuries during laparoscopic cholecystectomy: primary and long-term results from a single institution

et al. 2007

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Section: Discussionmentioning

confidence: 99%

Bile duct injuries during laparoscopic cholecystectomy: primary and long-term results from a single institution

et al. 2007

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“…According to Terblanche et al, 11 biliary-enteric anastomosis is effective in 90% of cases. According to Rossi and Tsao, 30 long-term results of EE are worse due to the higher stricture rate of 40-50%. However, after HJ method of reconstruction, bile flow into the alimentary tract is not physiological because the duodenum and upper part of the jejunum are excluded from bile passage.…”

Section: Discussionmentioning

confidence: 99%

Hepaticojejunostomy vs. End-to-end Biliary Reconstructions in the Treatment of Iatrogenic Bile Duct Injuries

Jabłońska

Lampe

Olakowski

et al. 2009

Journal of Gastrointestinal Surgery

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“…Unfortunately, in some cases the surgery is complicated by vasculobiliary injury. Iatrogenic injury of the biliary tract represents a complex problem for surgeon and patient [5]. Reconstruction consists in performing a biliodigestive anastomosis (BDA), but it represents a surgical challenge.…”

Section: Introductionmentioning

confidence: 99%

Improved Effects of Viral Gene Delivery of Human uPA plus Biliodigestive Anastomosis Induce Recovery from Experimental Biliary Cirrhosis

et al. 2004

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Gene therapy may represent a new avenue for the development of multimodal treatment for diverse forms of cirrhosis. This study explores the potential benefits of combining adenovirus-mediated human urokinase-plasminogen activator (AdHuPA) gene delivery and biliodigestive anastomosis to enhance the therapeutic efficacy of each treatment alone for cholestatic disorders resulting in secondary biliary cirrhosis. In an experimental model of secondary biliary cirrhosis, application of 6 x 10(11) vp/kg AdHuPA adenovirus vector resulted in 25.8% liver fibrosis reduction and some improvement in liver histology. The relief of bile cholestasis by a surgical procedure (biliodigestive anastomosis) combined with AdHuPA hepatic gene delivery rendered a synergistic effect, with a substantial 56.9 to 42.9% fibrosis decrease. AdHuPA transduction resulted in clear-cut expression of human uPA protein detected by immunohistochemistry and induction of up-regulation in the expression of metalloproteinases MMP-3, MMP-9, and MMP-2. Importantly, functional hepatic tests, specifically direct bilirubin, were improved. Also, hepatic cell regeneration, rearrangement of hepatic architecture, ascites, and gastric varices improved in cirrhotic rats treated with AdHuPA but not in counterpart AdGFP cirrhotic animals. We believe this might represent a novel therapeutic strategy for human cholestatic diseases.

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Biliary Reconstruction

Cited by 44 publications

References 18 publications

Bile duct injuries during laparoscopic cholecystectomy: primary and long-term results from a single institution

Bile duct injuries during laparoscopic cholecystectomy: primary and long-term results from a single institution

Hepaticojejunostomy vs. End-to-end Biliary Reconstructions in the Treatment of Iatrogenic Bile Duct Injuries

Improved Effects of Viral Gene Delivery of Human uPA plus Biliodigestive Anastomosis Induce Recovery from Experimental Biliary Cirrhosis

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