In this study, the effect of OpenDyslexic font on increasing the reading fluency and reading comprehension skills of students with dyslexia was investigated. For this purpose, the effect of OpenDyslexic font on increasing the reading speed, reading accuracy, prosodic reading levels, reading levels and reading comprehension levels of students with reading difficulties was examined. Three students with a diagnosis of "Learning Disability" and a subdiagnosis of "Mixed-Type Disorder in Scholastic Skills" participated in the study. Participants are 10 years old and fourth grade level. In the study, "Inter-Subject Multiple Probe Model", one of the single-subject research designs, was used. In order to collect the research data, texts suitable for the fourth grade level were used. At the beginning level of the research, the texts in the font used in the textbooks were studied, and in the application phase, the texts were converted to OpenDyslexic font. Research results show that OpenDyslexic font is effective in increasing reading fluency and reading comprehension level in all three students. There was an increase in participants' reading speed, reading accuracy, prosodic reading and reading comprehension skills. It is recommended to include texts prepared with OpenDyslexic font in school textbooks.