Biliopancreatic Diversion in a Renal Transplant Patient

Deogracias, Maite López; Domínguez‐Díez, Agustín; Palomar-Fontanet, Rosa; González-Noriega, Mónica; Rodrigo, Emilio; Fernández‐Fresnedo, Gema; Zubimendi, J.A; Olmedo, Francisco García; Gómez-Fleitas, Manuel; Arias, Manuel; Fernández-Escalante, Carlos

doi:10.1007/s11695-007-9097-z

Cited by 8 publications

(2 citation statements)

References 14 publications

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“…Cyclosporine is used in several diseases such as rheumatoid arthritis, psoriasis, and allogenic transplantation of the kidney, liver, heart, pancreas, etc. It is assimilated in the gastrointestinal tract, follows hepatic metabolization by the cytochrome P450 system, and its excretion is mostly biliary, with only 6% eliminated through the urinary tract [14,15]. In our case, we did not notice any interference in cyclosporine serum levels.…”

Section: Discussionsupporting

confidence: 40%

Intragastric Balloon Followed by Biliopancreatic Diversion in a Liver Transplant Recipient: A Case Report

et al. 2009

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Liver transplantation is a life-saving procedure for end-stage liver disease. In liver transplant recipients, morbid obesity influences post-operative survival and graft function. In 1996, our patient underwent a successful liver transplantation because of a HCV-related liver failure (body mass index (BMI) 31). Follow-up showed a functional graft and the development of severe obesity up to a BMI of 61 in January 2006. In January 2007, he was submitted to intragastric balloon therapy for 6 months, reaching a BMI of 54. In September 2007, he underwent a biliopancreatic diversion. During follow-up to March 2008, he reached a BMI of 42 with ameliorations of comorbidities. In May 2008, during a hospital admission, he suddenly died of a heart attack. Post mortem study revealed a myocardial infarction. This is the first world case report for this approach. According to our opinion, patient's death was not related to bariatric surgery.

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Section: Discussionsupporting

confidence: 40%

Intragastric Balloon Followed by Biliopancreatic Diversion in a Liver Transplant Recipient: A Case Report

et al. 2009

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“…Biliopancreatic diversion in the presence of a renal allograft has also been described by Deogracias [79]. The procedure produced good weight loss (85% of excess weight at 25 months post-procedure) and improved quality of life.…”

Section: Feasibility Of Bariatric Surgery In Renal Transplant Recipientsmentioning

confidence: 98%

Bariatric Surgery and Renal Function

2011

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Obesity causes a significant healthcare burden and has been shown to be an important risk factor in the development of cardiovascular disease, type 2 diabetes, and increasingly chronic kidney disease. Bariatric surgery is the most effective treatment for obesity and has been shown to drastically improve both blood pressure and diabetic control. However, the interaction of bariatric surgery and renal function is less clear. This review focuses on the effect of bariatric surgery on renal function both in the acute situation, with respect to acute kidney injury, and also on changes in renal function parameters post-bariatric surgery weight loss. The interaction of obesity, bariatric surgery, and nephrolithiasis as a precipitant of acute kidney injury will also be considered. The role of bariatric surgery in pre- and post-renal transplant recipients is discussed as well as possible mechanisms underlying the improvement in renal function.

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