Bilirubin levels and severe retinopathy of prematurity in infants with estimated gestational ages of 23 to 26 weeks

DeJonge, Mitchell H.; Khuntia, Annie; Maisels, M. Jeffrey; Bandagi, Amtul

doi:10.1016/s0022-3476(99)70336-7

Cited by 36 publications

(23 citation statements)

References 13 publications

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“…25 Dejonge revealed no significant difference regarding the average duration of phototherapy among mild and severe ROP groups, but found an association for ROP development with bilirubin levels in newborns at 23 to 26 weeks of gestational age. 26 In our study there was no relationship between oxygen therapy and ROP. In fact the role of oxygen has been overemphasized in the past and excessive oxygen administration has not been identified as an independent risk factor.…”

Section: Discussioncontrasting

confidence: 56%

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Incidence and Risk Factors of Retinopathy of Prematurity in Babol, North of Iran

Mikaniki

Ahmad

Mikaniki

2010

Ophthalmic Epidemiology

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Section: Discussioncontrasting

confidence: 56%

“…Mean BW in the ROP group was 1423.03 ± 332. 26 and birth weight less than 1500 (P = 0.001, OR = 3.846) were independent significant risk factors for the development of ROP (Table 3).…”

Section: Resultsmentioning

confidence: 99%

Incidence and Risk Factors of Retinopathy of Prematurity in Babol, North of Iran

Mikaniki

Ahmad

Mikaniki

2010

Ophthalmic Epidemiology

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“…This incidence is in line with other European cohorts but is high when compared to American cohorts (table 1). [6][7][8][9][10] This might at least partially be explained by the high incidence of white infants in European cohorts.…”

Section: Discussionmentioning

confidence: 99%

Threshold retinopathy at threshold of viability: the EpiBel study

Allegaert¹,

Coen²,

Devlieger³

2004

British Journal of Ophthalmology

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Aim: To describe incidence, co-morbidity characteristics, and risk factors associated with threshold retinopathy of prematurity (ROP) in survivors with a gestational age (GA) of (26 weeks at birth. Methods: Retrospective analysis of perinatal data of all inborn survivors in all perinatal centres of Belgium in the period 1999-2000 (EpiBel cohort) believed to be between 22 and 26 weeks GA at time of delivery. Data on survivors who did and survivors who did not develop threshold ROP were compared (x 2 , MannWhitney U) and logistic regression was performed. Results: Of 303 admitted infants 175 (58%) were discharged alive. Incidence of major retinopathy (>stage 3) and of threshold ROP was 25.5% and 19.8% in survivors. Associated central nervous abnormalities were documented in six (17%) and associated chronic lung disease in 19 (54%) threshold ROP infants. Threshold ROP without additional morbidity characteristics at discharge was documented in 14 (40%) infants. Besides often reported risk factors, renal insufficiency (creatinaemia.1.5 mg/dl) was a risk factor to develop threshold ROP (p,0.0015) (x 2 ). Days of respiratory support (OR 1.02; 95% CI 1.002 to 1.039), number of transfusions (OR 1.118; 95% CI 1.030 to 1.214), and renal insufficiency (OR 3.31; 95% CI 1.344 to 8.196) remained independent risk factors to develop threshold ROP in this cohort in a stepwise logistic regression model (MedCalc). Conclusions: Incidence of threshold ROP is high at the limits of viability. Renal insufficiency is a risk factor to develop threshold ROP in this cohort.

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“…In a study of 157 23-26 week gestation infants, however, no relation was found between TSB levels and retinopathy of prematurity. 24 More than 90% of extremely LBW infants (birth weights , 1000 g) receive phototherapy, and concern for the possible negative consequences of aggressive phototherapy has led the NICHHD Neonatal Research Network to initiate a prospective randomised trial to compare aggressive with conservative phototherapy in these infants (B Morris, personal communication, 2002). Table 4 shows the TSB levels for intervention with phototherapy and exchange transfusion in this continuing trial.…”

Section: Management Of Neonatal Jaundice In Preterm Neonatesmentioning

confidence: 99%