The production cross sections of neutron-rich isotopes of Mg, Al, Si, P, S, Cl, Ar, K, Ca, Sc, and Ti in the multinucleon transfer reactions 48 Ca(64 MeV/nucleon, 140 MeV/nucleon) + 181 Ta and 48 Ca(142 MeV/nucleon)+ nat W are estimated. A good agreement of the calculated results with the available experimental data confirms the mechanism of multinucleon transfer at almost peripheral collisions at intermediate energies. The global trend of production cross section with the charge (mass) number of target in reactions with 48 Ca beam is discussed for the future experiments.Projectile fragmentation at intermediate energies is a wellestablished method for the production of rare isotopes [1][2][3][4][5][6][7][8][9][10][11]. In addition to the fragmentation reactions the multinucleon transfer reactions are actively discussed to produce exotic nuclei. These binary reactions have been known for producing exotic nuclei for many years [12][13][14][15][16][17][18][19]. In the transfer reactions the excitation energies of the fragments are smaller than in the fragmentation reactions. The control of excitation energy of the reaction products in the binary processes is much simpler. So, the yields of exotic nuclei can be even larger in the transfer reactions than the yields in the high-energy fragmentation reactions in spite of the smaller experimental efficiency in the collection of exotic nuclei in the transfer reactions than in the fragmentation reactions. In Refs. [20] we have shown the possibility to produce the neutron-rich nuclei in the transfertype reactions at incident energies close to the Coulomb barrier. This process in the 238 U(5.5 MeV/nucleon) + 48 Ca reaction has been used to produce the odd and even neuron-rich Ca isotopes and study their low-lying states [21].As shown in Refs. [22,23], in the 209 Bi + 136 Xe and 197 Au + 208 Pb reactions at the lower boundary of the Fermi energy domain the total reaction cross section is almost entirely accounted for by binary collisions irrespective of a possible further disassembly of the two highly excited primary partners. The dissipative binary dynamics at these bombarding energies have been also observed in Refs. [24][25][26]. The observed influence of the target isospin on the final isospin of the projectile-like fragments and broadening of the projectilelike fragments charge distributions with increasing energy dissipation is similar to that encountered in damped reactions at lower bombarding energies of only a few MeV/nucleon above the Coulomb barrier. As clearly shown in Refs. [27][28][29][30][31][32][33][34], the transfer process is a very strong component for the projectile-like products in the peripheral collisions.The nucleon pickup products have been observed among the products of projectile fragmentation reactions at the bombarding energies above the Fermi energy: 48 Ca (55 MeV/ nucleon) + 181 Ta [1], 48 Ca(64 MeV/nucleon) + 181 Ta [9], 18 O(80 MeV/nucleon) + 27 Al, 181 Ta [35], 112 Sn (63 MeV/ nucleon) + nat Ni [2], 86 Kr(70 MeV/nucleon) + 27 Al [36], and pri...