Binding Capability and Non–biofouling Efficacy of Poly[2‐(methacryloyloxy)ethyl‐4‐pentynoate‐co‐oligo(ethylene Glycol) Methacrylate] Films on Gold Surfaces

Abstract

We demonstrated the binding capability and non‐biofouling efficacy of biotinylated, poly(MAEP‐co‐OEGMA) films using streptavidin and fibrinogen. The copolymeric films were synthesized on gold substrates without activation or passivation via the surface initiated‐controlled radical polymerization of MAEP and OEGMA in five different molar ratios, followed by biotinylation using “click” chemistry. The copolymeric film synthesized with MAEP at a mole fraction of 0.2 exhibited the best performance of surface plasmon resonance.

Non‐Biofouling Performance and Binding Capabilities of Amylose Film Coated on Glass Surface

“…Among the several coating techniques, surface‐initiated controlled radical polymerizations (SI‐CRPs) have been used to coat zwitterionic or PEG film on solid surfaces, because SI‐CRPs could control the thickness and roughness of polymeric film through the covalent bond formation 13–15 . However, SI‐CRPs require proficient skills to handle the multiple processes, such as the immobilization and characterization of a polymerization initiator on a surface and polymerization under anaerobic conditions 16 …”

Formation of Various Polymeric Films via Surface‐Initiated ARGET ATRP on Silicon Substrates

“…The surface modification of solid substrates with polymeric thin films has been recognized as a powerful tool to modulate chemical and physical properties at surface/interface and, as the result, to endow specific functionality to the substrates 1–6 . The surface functionalization with polymeric films/brushes ( i.e ., the surface‐grafting polymers) has been utilized in various research and industrial fields such as electronics, 7 catalysis, 8 cell surface engineering, 9 antibacterial coatings, 10,11 biosensors, membrane science, and so forth 12 .…”