Binding of anions in triply interlocked coordination catenanes and dynamic allostery for dehalogenation reactions

Abstract

Triply interlocked metal organic catenanes with several kinds of individual pockets enabled the possibility of encapsulating different anions, allowing the dynamic allostery between the unlocked/locked conformers to efficiently promote the dehalogenation reaction.

Positive Allosteric Control of Guests Encapsulation by Metal Binding to Covalent Porphyrin Cages

“…Many more complex multidomain regulatory proteins and biological machines that integrate multiple signaling events and long‐range coupled conformational modifications through homotropic or heterotropic binding events have shown to proceed also through allosteric mechanisms . Although the design of 3D hollow structures has led to selective receptors for guest encapsulation and promising molecular nanoreactors, their development as biomimetic allosteric receptors able to control guest complexation through large conformational changes remains a significant challenge . Such a control implies to integrate in the framework of the structure several components with defined regulation and guest binding functions.…”

“…[2,3] Althought he design of 3D hollow structures has led to selective receptors for guest encapsulation and promising molecular nanoreactors, their development as biomimetic allosteric receptors able to control guest complexation through large conformational changes remains as ignificant challenge. [25][26][27][28][29][30][31][32] Such ac ontrol implies to integrate in the framework of the structures everalc omponents with defined regulation and guest binding functions. Moreover,t he structure must ensure the preorganizationo ft he active components, the flexibility for conformational rearrangementsa nd should prevent direct interactions between the recognition and regulation sites.…”

Highly Selective Enamination of β‐ketoesters Catalyzed by Interlocked [Cu8] and [Cu18] Nanocages

“…Interlocked cages, in which components are held together by mechanical linkages, have attracted great attention due to their use as molecular motors, molecular knots, and molecular machines, and their potential applications in information processing and storage, host–guest chemistry, and catalysis, amongst others . Since the first interlocked cage consisting of two coordination M 3 L 2 cages (M=Pt, Pd) was reported in 1999, various interlocked coordination cages and purely organic interlocked cages have been reported, including [2]‐catenanes assembled from two interlocked cages, one dimensional (1D) polycatenanes constructed from a strand of interlocked cages, and three‐dimensional (3D) infinite polycatenates fabricated by multiple catenation of cages .…”

Coordinative-to-covalent transformation, isomerization dynamics, and logic gate application of dithienylethene based photochromic cages

“…One-pot component self-assembly of versatile coordination architectures has aroused great interest in recent years. In particular, via the synergetic formation of dynamic covalent imine bonds (C]N) and coordination bonds, a variety of fascinating structures have been constructed, including cages, [1][2][3][4][5][6][7][8][9][10][11][12] helicates, [13][14][15][16] capsules, [17][18][19][20] borromeates, [21][22][23] catenanes [24][25][26][27] and rotaxanes. [28][29][30][31] Multi-component self-assembly of pure covalent-organic cage-like architectures with well-dened complexity and integrity has been achieved, [32][33][34][35] but the use of metallo-components may provide further control of the process by preorientation through metal ion coordination.…”