Binding properties of herbicide chlorpropham to DNA: Spectroscopic, chemometrics and modeling investigations

Intercalation binding of food antioxidant butylated hydroxyanisole to calf thymus DNA

“…Hypochromism and a mild red shift of the spectra at 286 nm were observed upon the addition of increasing concentrations of ctDNA to the BHA solution, suggesting that BHA intercalated into ctDNA double-helix and was involved in a strong interaction in the molecular stack between the aromatic chromophore and the base pairs [40]. A similar observation has been found for the interaction of chlorpropham with ctDNA [41]. UV-vis absorption spectral data of BHA in the presence of different concentrations of ctDNA were used to calculate their apparent equilibrium binding constant (K b ) according to the Benesi-Hildebrand equation [17]:…”

Evaluation of interaction between imidazolium-based chloride ionic liquids and calf thymus DNA

“…DNA presents an absorption peak at 207 nm, owing to the presence of deoxyribose and phosphoric acids in its skeleton structure (Li et al, 2014). A distinct hypochromicity and a red shift appeared on the absorption spectra of ctDNA, adenine, and thymine at 210 nm with [C n mim]Cl (Fig.…”

“…The interaction of environmental pollutants with DNA has recently attracted interest. Several reports described the mechanism of interaction between DNA and environmental pollutants such as polycyclic aromatic hydrocarbon metabolites (Wei et al, 2010) and herbicides (Li et al, 2014). The interaction of DNA with ILs has also been investigated by spectroscopic and molecular docking study (Pabbathi and Samanta, 2015;Mishra et al, 2016).…”

Investigation on the interaction of letrozole with herring sperm DNA through spectroscopic and modeling methods

“…Fluorescence spectra provide vital information about the mechanism, constant and mode of binding. By contrast, the position or shape of the fluorescence spectra of letrozole did not change; thus, letrozole can interact with hsDNA through non-covalent bonds, rather than covalent bonds (24). The fluorescence intensity of letrozole consistently decreased with continuous hsDNA addition; this finding revealed a strong interaction between letrozole and hsDNA (22,23).…”