Bio-Alcamid: An Electron Microscopic Study After Skin Implantation

Formigli, Lucia; Zecchi, S.; Protopapa, Carmelo; Caporale, Domenico; Cammarota, N.; Lotti, Torello

doi:10.1097/01.prs.0000107746.58665.0a

Cited by 30 publications

(14 citation statements)

References 4 publications

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“…In vitro studies have also shown that it does not have any cytotoxic effects on human isolated lymphocytes as well as low interference with cell viability 21. Even electron microscopy revealed little evidence of inflammatory reactions in the vicinity of implantation on skin biopsies of healthy human volunteers 22. Clinical studies further confirmed Bio‐Alcamid as an ideal injectable filler with good patient results.…”

Section: Discussionmentioning

confidence: 93%

Large needle suction aspiration of permanent fillers

Wilson¹,

Ellis²

2011

The Laryngoscope

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Temporary injectable fillers have become so widely accepted within the cosmetic medical industry that permanent fillers with longer lasting effects are fast gaining popularity. Both patients and physicians alike have eagerly sought a product to minimize the inconvenience and cost of repeated injections. However, the fear is that the use of permanent fillers may lead to permanent problems. We describe here an in-office technique to remove permanent injectable fillers that achieves consistent, natural results with minimal risk of scarring.

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Section: Discussionmentioning

confidence: 93%

Large needle suction aspiration of permanent fillers

Wilson¹,

Ellis²

2011

The Laryngoscope

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“…A diferencia de otras sustancias de relleno utilizadas años atrás y hoy prohibidas en nuestro país (como la silicona fluida o líquida), el Bio-Alcamid ® es un material permanentemente estable, evitándose de este modo su migración tisular. 6 Otra importante ventaja desarrollada por este compuesto es su radiotransparencia, lo que evita que se interfiera el resultado de determinadas pruebas diagnósticas.…”

Section: Discussionunclassified

Utilización de polialcamida en cirugía reconstructiva y estética facial

Gil

Carrasco

Ruiz

et al. 2007

Rev Esp Cirug Oral y Maxilofac

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Resumen: Objetivos. Presentar nuestra experiencia en el manejo y aplicación de biomateriales no reabsorbibles (poliaquilamida) en pacientes con defectos faciales de diversa etiología. Material y métodos. Empleamos poliaquilamida (Bio-Alcamid ® ) en un total de catorce pacientes. Cuatro pacientes presentaban distintos grados de lipodistrofia facial secundaria a tratamientos antiretrovirales. Otros cuatro, consultaron porque deseaban mejorar el aspecto de su perfil labial. Tres pacientes habían sido sometidos con anterioridad a exéresis oncológicas, y otros dos mostraban defectos faciales derivados de traumatismos. Finalmente, un paciente presentaba un defecto nasal, secuela de una rinoplastia previa. Resultados. Todos los pacientes mostraron un índice muy elevado de satisfacción. No se registraron complicaciones graves. Queremos señalar la estabilidad y durabilidad del implante. Conclusiones. La seguridad y sencillez de esta técnica asociada al alto grado de satisfacción manifestado por los pacientes, animan al empleo de estas sustancias en la corrección de defectos faciales de diversa etiología.

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“…This completely surrounds the gel, isolating it from the host tissues, and making it a type of endogenous prosthesis. 22 According to the Italian manufacturer, Polymekon, the encapsulated prosthesis has the potential for later extraction from surrounding tissue. To date, reactions to polyacrylamide gels appear to be rare and have not been reported in HLS-treated patients.…”

Section: Discussionmentioning

confidence: 99%

“…To date, reactions to polyacrylamide gels appear to be rare and have not been reported in HLS-treated patients. 22 The compound has been used since 2000 in over 20 countries and does not require any sensitization test as no allergic reaction has ever been reported. 23 Although the gel has been extensively evaluated in a 2000 patient study that demonstrated its safety, efficacy, and biocompatibility, 24 there have been anecdotal reports of occasional poorly defined adverse reactions.…”

Section: Discussionmentioning

confidence: 99%

Use of a Biopolymer Polyalkylimide Filler for Facial Lipodystrophy in HIV-Positive Patients Undergoing Treatment with Antiretroviral Drugs

Treacy¹,

Goldberg

2006

Dermatologic Surgery

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The immediate benefits of a polyalkylimide gel in the correction and restoration of facial contour in subjects having severe HIV-related facial lipodystrophy were demonstrated. This improvement was still noted at 18 months. The efficacy, ease of injection, and safety profile of polyalkylimide gel make this filling material a potentially attractive treatment for lipodystrophy. These data must be tempered with the need for significant further safety studies to determine whether this long-term filler has a safety profile consistent with other currently popular fillers.

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Bio-Alcamid: An Electron Microscopic Study After Skin Implantation

Cited by 30 publications

References 4 publications

Large needle suction aspiration of permanent fillers

Large needle suction aspiration of permanent fillers

Utilización de polialcamida en cirugía reconstructiva y estética facial

Use of a Biopolymer Polyalkylimide Filler for Facial Lipodystrophy in HIV-Positive Patients Undergoing Treatment with Antiretroviral Drugs

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