Bio-antimutagenic effect of S-methyl methane thiosulfonate separated from the vegetable homogenates of Cruciferae Brassica and Liliaceae Allium species

Matsuo, T.; Shimoi, Kayoko; Nakamura, Yoshimasa; Tomita, Isao

doi:10.1016/0165-1161(95)90129-9

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“…Hence, this dose was selected for further study. Antimutagenic potential of various vegetables 591 from Brassicaceae and Liliaceae families has been investigated against UV-induced mutagenesis, whereas some other vegetable extracts were reported to inhibit mutations caused by several indirect acting chemical mutagens, though they were reportedly ineffective against direct acting chemical mutagens (Nakamura et al 1995(Nakamura et al , 1996Kusamran et al 1998).…”

Section: Effect Of Uv Exposure On Cell Viability and Mutagenicitymentioning

confidence: 99%

Variety-based variation in the antimutagenic potential of various vegetables and lack of its correlation with their antioxidant capacity

Bandyopadhyay

Gautam

Sharma

2013

International Journal of Food Sciences and Nutrition

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As mutation causes many life-threatening diseases including cancer, a diet enriched with specific vegetables having potential to reduce mutagenesis possesses immense significance. In this study, 41 commonly used vegetables from diverse botanical taxa were evaluated and compared for their relative antimutagenic potential using standard assays [Escherichia coli RNA polymerase β (rpoB)-based Rif(S) → Rif(R) assay and Ames test] against known mutagens (UV, gamma radiation, 4-nitroquinoline-N-oxide and ethylmethanesulphonate). Significant differences in antimutagenicity were observed even among the cultivars within the same species, as well as at other phylogenetic levels such as genus or family. The effect of cooking in terms of boiling (aquathermal treatment), on the antimutagenicity of these vegetables, was also investigated. In majority of the cases, aquathermal treatment did not affect the antimutagenic potential. The antimutagenicity of these vegetables was not found to correlate well with their antioxidant properties.

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Section: Effect Of Uv Exposure On Cell Viability and Mutagenicitymentioning

confidence: 99%