Bio-Farms for Nutraceuticals

doi:10.1007/978-1-4419-7347-4

Cited by 26 publications

(1 citation statement)

References 900 publications

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“…In the last years, the investigation of cyanobacteria attracts a considerable attention due to their environmental and biotechnological importance. New applications of cyanobacterial communities appear in biotechnology (i.e., production of biofuel, agricultural fertilizers, pharmaceutics, and food additives ultraviolet protection compounds) [1][2][3][4][5] and biosensing [6][7][8][9]. Large-scale industrial production of the cyanobacterial products requires optimization and more detailed control of incubation conditions in order to increase productivity.…”

Section: Introductionmentioning

confidence: 99%

Studying Cyanobacteria by Means of Fluorescence Methods: A Review

Grigoryeva¹

2020

Fluorescence Methods for Investigation of Living Cells and Microorganisms

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Self-fluorescence is a powerful tool for investigation of living photosynthetic microorganisms. Since the physiological state of such microorganisms is closely related to the operation and activity of photosynthetic system; thus, any variations in spectroscopic properties of their self-fluorescence indicate the changes in their physiological state. Cyanobacteria (or blue green alga) are one of the most widespread photosynthetic organisms in nature, and the ecological aspect in their investigation is quite valuable. On the other hand, thousands of strains belonging to different cyanobacterial species are cultivated in biolaboratories all over the world for different biotechnological applications such as biofuel cells, food production, pharmaceuticals, and fertilizers. Thus, the novel noninvasive methods of their investigation are quite important for on-line monitoring of cyanobacterial cultures. In this chapter, several fluorescence techniques are presented for investigation of living cyanobacterial cells and cultures.

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Section: Introductionmentioning

confidence: 99%

Studying Cyanobacteria by Means of Fluorescence Methods: A Review

Grigoryeva¹

2020

Fluorescence Methods for Investigation of Living Cells and Microorganisms

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Plant Pharmacogenomics: From Drug Discovery to Personalized Ethnomedicine

Babar

Zaidi

Gul

2015

PlantOmics: The Omics of Plant Science

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Anacardic Acids from Cashew Nuts Prevent Behavioral Changes and Oxidative Stress Induced by Rotenone in a Rat Model of Parkinson’s Disease

et al. 2018

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Anacardic acids (AAs) are alkyl phenols mainly presenting in cashew nuts. The antioxidant effects of these compounds have been an area of interest in recent research, with findings suggesting potential therapeutic use for certain diseases. Nevertheless, none of these studies were performed in order to test the hypothesis of whether anacardic acids are capable of preventing behavioral changes and oxidative stress induced by the pesticide rotenone in experimental model of Parkinson's disease. In our research, adult male rats were treated orally with AAs (1, 3, 10, 25, 50, or 100 mg/kg/day) 1 h before rotenone (3 mg/kg; s.c.) for five consecutive days. The behavioral testing strategies, including tests for general locomotor activity (open field), motor coordination (rotarod), and spatial memory performance (elevated T-maze), were carried out. Lipoperoxidation levels and total superoxide dismutase (t-SOD) activity, as well as cytoplasmic and mitochondrial SOD gene expression, were assessed in the substantia nigra (SN), striatum, and cerebral cortex. The results showed that AAs dose-dependently prevented the rotenone-induced learning and motor impairment from 10 mg/kg/day. AAs also precluded rotenone-induced lipoperoxidation in all doses, acting directly on the mitochondria, and improved the t-SOD activity in the doses 25-100 mg/kg/day. AAs per se (100 mg/kg/day) increased SOD gene expression and t-SOD activity. Our findings indicate that the oral administration of AAs prevents rotenone-induced behavioral changes and oxidative stress, in part due to a modulatory action on the mitochondria and SOD gene expression. These data suggest that AAs have promising neuroprotective action against degenerative changes in Parkinson's disease.

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Bio-Farms for Nutraceuticals

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Cited by 26 publications

References 900 publications

Studying Cyanobacteria by Means of Fluorescence Methods: A Review

Studying Cyanobacteria by Means of Fluorescence Methods: A Review

Plant Pharmacogenomics: From Drug Discovery to Personalized Ethnomedicine

Anacardic Acids from Cashew Nuts Prevent Behavioral Changes and Oxidative Stress Induced by Rotenone in a Rat Model of Parkinson’s Disease

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