Bio-Heat Transfer Simulation of Square and Circular Array of Retinal Laser Irradiation

Abstract

Pan Retinal photocoagulation (PRP), a retinal laser surgical process, is simulated using a three-dimensional bio-heat transfer numerical model. Spots of two different type of array, square array of 3 × 3 spots and a circular array of six spots surrounding a central spot, are sequentially irradiated. Pennes bio-heat transfer model is used as the governing equation. Finite volume method is applied to find the temperature distribution due to laser irradiation inside the human eye. Each spot is heated for 100 ms and subsequently cooled for 100 ms with an initial laser power of 0.2 W . Based on the outcome of temperature distribution, the laser is pulsated in subsequent simulations to reduce the average peak temperature of spots to minimize the temperature induced cell damage. A method to reduce the laser power to attain the peak temperature towards photocoagulation temperature (60• C) is also presented.

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“…Therefore, the limiting factor is MPET which results in 47.90 mW entering the The heat capacity, thermal conductivity, density, perfusion rate and self-heat of the iris anterior border layer, stroma and pigment epithelium were taken respectively from the cornea, choroid and retinal pigment epithelium, due to their biological similarity. The parameters were obtained from references [87][88][89][90][91][92][93] . Male 133 Ti Male 115 Female 137 Male 108 Male 122 Male 133 Male 141 Ti Male 123 Male 117 Male 130 Male 103 Male 131 Male 108 Ti Female 127 Male 119 Male 108 Male 132 Female 116 Ti Female 134 Male 148 Male 108 Male 136 Female 114 Ti Pharmacology Male 123 Male 152 Male 117 Ti Fig.…”

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“…Li et al [9] simulated the 2D and 3D models of an eye and investigated the effect of hyperthermia treatment on healthy eye tissues. Narasimhan and Jha [10] modeled Pan Retinal Photocoagulation (PRP), a retinal laser surgical process, and found eye temperature distribution under different conditions. Abouali et al [11] used a computational modeling approach to study the unsteady ow in the vitreous cavity due to saccadic eye movement.…”

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“…The parameters were obtained from references[94][95][96][97][98][99][100] . The heat capacity, thermal conductivity, density, perfusion rate and self-heat of the iris anterior border layer, stroma, and pigment epithelium were taken respectively from the cornea, choroid and retinal pigment epithelium, due to their biological similarity.…”