Bio-materials and factors affecting periodontal regeneration: An overview

Abstract

The aim of periodontal regenerative therapy is to restore original architecture and function of lost periodontal tissues, as a result of trauma or following destructive periodontal diseases. This review includes the biological principles and efficacy and effectiveness of different biomaterials and factors affecting periodontal regeneration. Various human clinical trials showed a successful periodontal regeneration with different biomaterials. However, postoperative plaque control is one of the key factors influencing periodontal healing following regenerative periodontal therapy. A strong native regenerative potential of the periodontium can be conciliated by local and systemic factors.