Bio-Mediated Production and Characterisation of Magnetic Nanoparticles Using Fruit Peel Extract

Yusefi, Mostafa; Yee, Ong Su; Shameli, Kamyar

doi:10.37934/jrnn.1.1.5361

Cited by 8 publications

(7 citation statements)

References 23 publications

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“…It is also worth mentioning that several studies have used plant-based stabilizer/capping agents in the green synthesis methods of MNPs. [103][104][105][106]…”

Section: Biosynthesis Methodsmentioning

confidence: 99%

How Magnetic Composites are Effective Anticancer Therapeutics? A Comprehensive Review of the Literature

Yusefi¹,

Shameli²,

Jahangirian³

et al. 2023

IJN

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Chemotherapy is the most prominent route in cancer therapy for prolonging the lifespan of cancer patients. However, its non-target specificity and the resulting off-target cytotoxicities have been reported. Recent in vitro and in vivo studies using magnetic nanocomposites (MNCs) for magnetothermal chemotherapy may potentially improve the therapeutic outcome by increasing the target selectivity. In this review, magnetic hyperthermia therapy and magnetic targeting using drug-loaded MNCs are revisited, focusing on magnetism, the fabrication and structures of magnetic nanoparticles, surface modifications, biocompatible coating, shape, size, and other important physicochemical properties of MNCs, along with the parameters of the hyperthermia therapy and external magnetic field. Due to the limited drug-loading capacity and low biocompatibility, the use of magnetic nanoparticles (MNPs) as drug delivery system has lost traction. In contrast, MNCs show higher biocompatibility, multifunctional physicochemical properties, high drug encapsulation, and multi-stages of controlled release for localized synergistic chemo-thermotherapy. Further, combining various forms of magnetic cores and pH-sensitive coating agents can generate a more robust pH, magneto, and thermo-responsive drug delivery system. Thus, MNCs are ideal candidate as smart and remotely guided drug delivery system due to a) their magneto effects and guideability by the external magnetic fields, b) on-demand drug release performance, and c) thermo-chemosensitization under an applied alternating magnetic field where the tumor is selectively incinerated without harming surrounding non-tumor tissues. Given the important effects of synthesis methods, surface modifications, and coating of MNCs on their anticancer properties, we reviewed the most recent studies on magnetic hyperthermia, targeted drug delivery systems in cancer therapy, and magnetothermal chemotherapy to provide insights on the current development of MNC-based anticancer nanocarrier.

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“…It is also worth mentioning that several studies have used plant-based stabilizer/capping agents in the green synthesis methods of MNPs. [103][104][105][106]…”

Section: Biosynthesis Methodsmentioning

confidence: 99%

How Magnetic Composites are Effective Anticancer Therapeutics? A Comprehensive Review of the Literature

Yusefi¹,

Shameli²,

Jahangirian³

et al. 2023

IJN

Self Cite

View full text Add to dashboard Cite

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“…This was probably due to the effects of Brownian motion, whereby the nanoparticles were agitated randomly due to the increased fluid velocity around them. Brownian motion is the intercollision between nanoparticles and their surroundings, represented in this case by the base fluids and microchannel walls [60]. Higher flow rates elevated the inertial force in the fluid, leading to vigorous nanoparticle movement within the fluid.…”

Section: Mchs Heat Transfer Coefficient and Nusselt Numbermentioning

confidence: 99%

Thermal and hydraulic performance of Al alloy-based 3D printed triangular microchannel heatsink governed by rough walls with graphene and alumina nanofluids as working liquid

Nadarajah,

Mohamed,

Abdullah

et al. 2024

J. Micromech. Microeng.

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Microchannel heat sinks (MCHS) are known for providing enhanced cooling performance but their fabrication requires complex and multi step processes. The recent development of additive manufacturing has enabled the fabrication of state-of-art monolithic structures that had been impossible to build using conventional methods. In this work, a monolithic cross-flow triangular cross-section microchannel heat sink was fabricated from aluminum alloy (AlSi10Mg) using the Direct Metal Laser Sintering (DMLS) process. The microchannel wall surface roughness was measured and the cross-section shrinkage of the microchannels was compared with the initial design hydraulic diameter of 500 µm - 1 000 µm., The MCHS with an initial design hydraulic diameter of 750 µm possessed a relative wall surface roughness, Ra of 7.7%. The triangular cross-section hydraulic diameter underwent a shrinkage of 15.2% and 5.3% in terms of the reduction in angle between adjacent side alloys. Experiments were conducted for Reynolds numbers between 50 and 275 with nanofluids containing graphene and Al2O3 nanoparticles in water/water +10% ethylene glycol; these were compared with their respective base fluids. For this range of Reynolds numbers, with water as coolant, the rough wall surface elevated the friction factor to least double that of smooth microchannels. The Poiseuille number indicated that flow was laminar developed with base fluid and laminar developing with nanofluid as coolant. Despite providing the lowest thermal resistance, the graphene nanoparticles in water created the greatest pressure drop leading to a reduced performance coefficient. Al2O3 nanoparticles in water/water +10% Ethylene glycol were found to have 7.7% and 20% better performance coefficients than their respective base fluids.

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“…Nanoparticles have high stability and a long storage time. In another publication by this group of scientists, they demonstrated that the extract of Garcinia Mangostana fruit peel could be used as a bio-stabilizer and capping agent to enhance physicochemical properties and stability of Fe 3 O 4 nanofluid [8].…”

Section: Green Synthesis Of Hybrid Magnetic-semiconductor Oxides Nano...mentioning

confidence: 99%

Hybrid Magnetic-Semiconductor Oxides Nanomaterial: Green Synthesis and Environmental Catalytic

Nguyen¹,

Vu²,

Nguyễn³

2023

Photocatalysts - New Perspectives

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Semiconductor oxide nanoparticles with various properties are used in applications such as photocatalysis, lithium-ion batteries, antimicrobial materials, magnetic and antibacterial materials, sensors, thermally conductive and anti-ferromagnetic films and photocatalysis. Coprecipitation, sol-gel, electrospray synthesis, laser ablation, hydrothermal and green synthesis methods have been developed for the synthesis of semiconductor oxide nanoparticles. The photocatalytic treatment method is environmentally friendly, thorough, and has high efficiency. Hybrid magnetic-Semiconductor oxide nanoparticles materials are aggregated. This results in the combination of the superparameters of the iron oxide nanosystem and the ability to rapidly adsorb pollutants and separate them from environmental water, solid. This is due to characteristic properties such as low superparameter, low toxicity, low electrical conductivity, and large specific surface area. In addition, biosynthesis has attracted attention because it takes advantage of nonhazardous, environmentally friendly biological systems like bacteria, fungi, leaves, vitamins, and yeast to synthesize metal oxide nanopartilces and combined with sonosumbers to increase the dispersion of the system, reduce the size of the catalytic particles, and reduce the reaction time.

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Bio-Mediated Production and Characterisation of Magnetic Nanoparticles Using Fruit Peel Extract

Cited by 8 publications

References 23 publications

How Magnetic Composites are Effective Anticancer Therapeutics? A Comprehensive Review of the Literature

How Magnetic Composites are Effective Anticancer Therapeutics? A Comprehensive Review of the Literature

Thermal and hydraulic performance of Al alloy-based 3D printed triangular microchannel heatsink governed by rough walls with graphene and alumina nanofluids as working liquid

Hybrid Magnetic-Semiconductor Oxides Nanomaterial: Green Synthesis and Environmental Catalytic

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