“…However, we have not found any reports of pesticides affecting serine protease activity. Pesticides that are known to be protease inhibitors potentially might also interfere with melanization, such as the extract from seeds of the tree legume, Acacia senega (Babu and Subrahmanyam, 2010). Conversely, insecticide resistant strains of the mosquito, Culex pipiens, possess high serine protease activity, expressing up to three times the levels of activities found in non-resistant strains (Gong et al, 2005;Yang et al, 2008).…”