Bioaccessibility and potential bioavailability of phenolic compounds from achenes as a new target for strawberry breeding programs

Ariza, M.T.; Reboredo‐Rodríguez, Patricia; Cervantes, L.; Soria, C.; Martínez-Ferri, Elsa; González-Barreiro, C.; Cancho-Grande, B.; Battino, Maurizio

doi:10.1016/j.foodchem.2017.11.105

Cited by 81 publications

(52 citation statements)

References 33 publications

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“…The strawberry and achenes fractions used in the present study were previously characterized by our group [16]. Phenolic acids and hydrolysable tannins (36.65 ± 1.38 mg/100 g whole fruit), along with anthocyanins (33.27 ± 0.72 mg/100 g whole fruit), were the main families identified in the raw strawberry extract (RF), followed by flavanols (7.72 ± 0.29 mg/100 g whole fruit) and flavonols (6.49 ± 0.03 mg/100 g whole fruit).…”

Section: Resultsmentioning

confidence: 99%

“…Anthocyanins are absorbed mostly in their intact glycosidic or methylated forms, and are rapidly distributed into the circulatory system (within 0.25–2 h after ingestion) [38,40]. Their absorption mainly occurs in the stomach [42], while the environment of the small and large intestines (largely at neutral pH) do not favor their stability [16,38,39]. Furthermore, it has been suggested that a rapid degradation of these compounds within the gastrointestinal tract [38,40] and by the gut microbiota is likely to modify the anthocyanins’ molecular structures into phenolic acids, although modification by the small intestine conditions is more difficult to assess and remains yet to be described [38].…”

Section: Discussionmentioning

confidence: 99%

“…However, we previously identified and quantified several bioactive compounds in achenes extracts subjected to an in vitro digestion process, which suggested the successful release of these phytochemicals from this matrix [15,16]. …”

Section: Discussionmentioning

confidence: 99%

“…In fact, the intestinal digested fractions (IF, IAC), where no anthocyanins were detected [16], also presented a positive biological activity. Generally, the protective effects of strawberry and many other berries have been attributed to this group of compounds [7,43,44]; however, our results indicated that other families, such as phenolic acids and hydrolysable tannins (mainly ellagic acid) or flavonols (such as myricetin, quercetin, and kaempferol), can also contribute to their bioactivity.…”

Section: Discussionmentioning

confidence: 99%

“…These two different tissues (flesh and achenes) significantly differ in terms of chemical composition and antioxidant capacity [14,15,16]. While the biological activity of the complete fruit or its isolated phenolic compounds has been widely studied, to the best of our knowledge, there are no published works that evaluate the beneficial properties of the achenes separately.…”

Section: Introductionmentioning

confidence: 99%

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Strawberry and Achenes Hydroalcoholic Extracts and Their Digested Fractions Efficiently Counteract the AAPH-Induced Oxidative Damage in HepG2 Cells

Ariza

Forbes‐Hernández

Reboredo‐Rodríguez

et al. 2018

IJMS

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Strawberry fruits are highly appreciated by consumers worldwide due to their bright red color, typical aroma, and juicy texture. While the biological activity of the complete fruit has been widely studied, the potential beneficial effects of the achenes (commonly named seeds) remain unknown. In addition, when raw fruit and achenes are consumed, the digestion process could alter the release and absorption of their phytochemical compounds, compromising their bioactivity. In the present work, we evaluated the protective effects against oxidative damage of nondigested and digested extracts from strawberry fruit and achenes in human hepatocellular carcinoma (HepG2) cells. For that purpose, cells were treated with different concentration of the extracts prior to incubation with the stressor agent, AAPH (2,2′-azobis(2-amidinopropane) dihydrochloride). Subsequently, intracellular accumulation of reactive oxygen species (ROS) and the percentage of live, dead, and apoptotic cells were determined. Our results demonstrated that all the evaluated fractions were able to counteract the AAPH-induced damage, suggesting that the achenes also present biological activity. The positive effects of both the raw fruit and achenes were maintained after the in vitro digestion process.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Strawberry and Achenes Hydroalcoholic Extracts and Their Digested Fractions Efficiently Counteract the AAPH-Induced Oxidative Damage in HepG2 Cells

Ariza

Forbes‐Hernández

Reboredo‐Rodríguez

et al. 2018

IJMS

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Effects of distribution of sugars and organic acids on the taste of strawberries

Ikegaya

Toyoizumi

Ohba

et al. 2019

Food Science & Nutrition

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The concentrations of sugars and organic acids as well as the total soluble solid (TSS) in different parts of the strawberry fruit were characterized. The data were used to create simulated fruit juice jellies, in order to clarify how the sugar and organic acid levels affect the taste. Such an approach eliminates the influence of external factors such as size, color, and texture when using real fruits in sensory evaluations. Further, the use of a jelly allowed us to simulate the concentration differences between various parts of the fruit. In the strawberry fruit, the sugar content is higher in the apex than in the peduncle; however, the level of organic acids is the same throughout. It was revealed that the sweetness and sourness in the apex and peduncle could be sufficiently recognized by humans as tastes. Also, a layered jelly sample replicating the sugar and acid distribution in real strawberry was perceived as less sweet and more sour, compared to a homogeneous one with the same overall composition. The likely reason is that the sourness in the peduncle is accentuated by the low TSS level, which decreases the TSS/total organic acid ratio that affects the sweetness/sour perceptions. Based on these results, factors for the appropriate sensory evaluation of fresh fruits in general were considered. Specifically, the distribution of sugars and organic acids in the fruit should be analyzed first, and bite‐sized parts with concentrations close to the average provide the most accurate evaluation results.

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Comparison of Polyphenol Compounds of Strawberry Cultivars with Their Progeny

Sarıdaş

Ağçam

Bircan³

et al. 2022

Erwerbs-Obstbau

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Bioaccessibility and potential bioavailability of phenolic compounds from achenes as a new target for strawberry breeding programs

Cited by 81 publications

References 33 publications

Strawberry and Achenes Hydroalcoholic Extracts and Their Digested Fractions Efficiently Counteract the AAPH-Induced Oxidative Damage in HepG2 Cells

Strawberry and Achenes Hydroalcoholic Extracts and Their Digested Fractions Efficiently Counteract the AAPH-Induced Oxidative Damage in HepG2 Cells

Effects of distribution of sugars and organic acids on the taste of strawberries

Comparison of Polyphenol Compounds of Strawberry Cultivars with Their Progeny

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