Bioaccumulation of metals and effects of a landfill in small mammals. Part II. The wood mouse, Apodemus sylvaticus

Sánchez-Chardi, Alejandro; Peñarroja-Matutano, Cristina; Ribeiro, Ciro Alberto de Oliveira; Nadal, J.

doi:10.1016/j.chemosphere.2007.06.047

Cited by 89 publications

(57 citation statements)

References 39 publications

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“…Most data concerning the toxic effects of pollutants on the structure and function of organs come from experiments in laboratory animals exposed to a single compound, such as heavy metals (Damek-Poprawa and Sawicka-Kapusta, 2004;Koyu et al, 2006), and less frequently to complex mixtures, such as rivers. Contaminated rivers often contain a wide variety of organic and inorganic pollutants, including potentially toxic metals such as Pb, Cd, Fe, Zn, Cu, Mn, Mo, and Cr (Sánchez-Chardi et al, 2007). Oxidative stress may be attributed to these elements, producing a variety of alterations in tissues (Jadhav et al, 2007 ).…”

Section: Discussionmentioning

confidence: 99%

A multibiomarker approach in rats to assess the impact of pollution on Sinos River, Southern Brazil

et al. 2010

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The aim of this study was to determine the feasibility of combining water quality analysis with different biomarkers to characterise the relationship between anthropogenic contamination and biotic response in the Sinos River, southern Brazil. Wistar rats were studied using three biomarkers combined with physical, chemical and microbiological analysis to assess the effects of pollution at four sampling sites. The induction of oxidative stress was quantified by MDA levels in peripheral blood, lymphocyte DNA damage was determined using the comet assay, and histopathological changes were analysed in the liver. After sampling, animals were allowed to drink the river water during a 48 hours period. No increase in oxidative stress and DNA damage was observed. However, liver damage was observed in the animals exposed to water samples, indicating that the Sinos River is contaminated with hepatotoxic substances. Water analyses confirmed that water quality decreased downriver.Keywords: genotoxicity, pollution, biomarkers, oxidative stress, tissue damage. Análise de múltiplos biomarcadores em ratos para determinar o impacto da poluição do rio dos SinosResumo O objetivo deste estudo foi determinar a viabilidade de combinar a análise da qualidade da água com o estudo de biomarcadores para caracterizar a relação entre contaminação antropogênica e resposta biótica no rio dos Sinos, sul do Brasil. Ratos Wistar machos foram estudados usando três biomarcadores combinados com análises físicas, químicas e microbiológicas para determinar os efeitos da poluição em quatro locais de amostragem de água. A indução do estresse oxidativo foi quantificada pelos níveis de MDA no sangue periférico, o dano do DNA linfocitário foi determinado usando o ensaio cometa, e as alterações histopatológicas foram analisadas no fígado. As amostras da água do rio dos Sinos (dos quatro pontos selecionados) foram administradas por via oral (como água para beber) por 48 horas. Nenhum aumento do estresse oxidativo ou do dano do DNA foi observado. Entretanto, dano do tecido hepático foi verificado nos animais expostos à ingestão das amostras da água, indicando que o rio dos Sinos está contaminado com substâncias hepatotóxicas. As análises das amostras de água confirmaram a redução da qualidade da água em direção à foz do rio.Palavras-chave: genotoxicidade, poluição, biomarcadores, estresse oxidativo, dano tecidual.

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Section: Discussionmentioning

confidence: 99%

A multibiomarker approach in rats to assess the impact of pollution on Sinos River, Southern Brazil

et al. 2010

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“…Moreover, some species may be opportunistic and HM residues may serve a protection mechanism against their predators [38]. Other parameters used as population level biomarkers are: residual index "RI" (linear regression between body weight and body length without tail) and kidney size proportion.…”

Section: Heavy Metal Bioaccumulation Effects On Health Of Terrestrialmentioning

confidence: 99%

“…RI is used as "energy reserve" measure. Individuals with positive RI values are considered as better fitted individuals, and the increase in kidney relative weight suggest the presence of a stressor [38].…”

Section: Heavy Metal Bioaccumulation Effects On Health Of Terrestrialmentioning

confidence: 99%

Heavy Metal Pollution as a Biodiversity Threat

Tovar-Sánchez¹,

Hernández-Plata²,

Santoyo-Martínez³

et al. 2018

Heavy Metals

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Heavy metals exert their toxic effects through different mechanisms. Lately, increasing attention has been focused on understanding the long-term ecological effects of chronically exposed populations and communities and their consequences to the ecosystem. The long-term exposure to heavy metals in the environment represents a threat to wild populations, affecting communities and putting ecosystem integrity at risk. Therefore, this type of exposure represents a threat to biodiversity. In the field, metal exposure is generally characterized by low doses and chronic exposures. This type of exposure exerts alterations across levels of biological organization. Distribution and abundance of populations, the community structure and the ecosystem dynamics may be altered. This chapter will focus on how chronically metal exposures in the field affect negatively populations and communities becoming a threat to biodiversity. Also, attention is put on the tools that enable to characterize and analyze the detrimental effects of heavy metal exposure on wild populations. Hence, the use and development of biomarkers in ecotoxicology will be discussed.

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“…Heavy metals, similarly to other pollutants, are worldwide distributed into the environment and can cause toxic effects in the biota. Information about these effects in wild mammals is limited despite that it may be relevant to predict environmental risk (Hamers et al 2006, Sanchez-Chardi et al 2007. Therefore, biomonitoring pollution through wild animals is useful for the assessment of environmental quality.…”

Section: Introductionmentioning

confidence: 99%

Parasite fauna of rodents (Murinae) from El Hierro (Canary Islands, Spain): a multidisciplinary approach

Feliú

López

Gómez

et al. 2012

Acta Parasitologica

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The parasite fauna (protozoa, helminths and insects) of the two most widespread Murinae rodents in El Hierro (Canary Islands, Spain), the black rat (Rattus rattus) and the house mouse (Mus musculus domesticus) was studied. Faunistic, ecological, ecotoxicological data, as well as information on the biology of some nematode parasites of R. rattus are provided. The present work is unprecedented in the Canary Islands, and provides the first data on the parasite biodiversity in Murinae from the archipelago. Concerning to parasitofaunas stands out: a) impoverishment of biodiversity of helminths respect of which have the same hosts in other islands; b) increasing the number of species of Siphonaptera, even compared with flea species that parasitize the same hosts from continental biotopes.

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Bioaccumulation of metals and effects of a landfill in small mammals. Part II. The wood mouse, Apodemus sylvaticus

Cited by 89 publications

References 39 publications

A multibiomarker approach in rats to assess the impact of pollution on Sinos River, Southern Brazil

A multibiomarker approach in rats to assess the impact of pollution on Sinos River, Southern Brazil

Heavy Metal Pollution as a Biodiversity Threat

Parasite fauna of rodents (Murinae) from El Hierro (Canary Islands, Spain): a multidisciplinary approach

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