Bioaccumulation, subcellular distribution and toxicity of sediment-associated copper in the ragworm Nereis diversicolor: The relative importance of aqueous copper, copper oxide nanoparticles and microparticles

Nanomaterials in the environment: Behavior, fate, bioavailability, and effects—An updated review

“…For example, distinguishing newly accumulated Cu or Zn from background levels in organisms is difficult unless extremely high (and thus environmentally irrelevant) exposure concentrations are used (Dybowska et al 2011;Misra et al 2012). The application of tracer techniques can overcome this complication (Zhao and Wang 2010;Croteau et al 2011aCroteau et al , 2014Ramskov et al 2015;Thit et al 2015). For example, Croteau et al (2014) used isotopically labeled Ag NMs to characterize Ag uptake rates in the freshwater snail L. stagnalis across a wide range of aqueous and dietary exposure concentrations.…”

“…It is now clear that there are nanospecific aspects to the bioavailability and toxicity of NMs. In vivo, significantly different biouptake rates (Croteau et al 2011bKhan et al 2012Khan et al , 2013aKhan et al , 2013bThit et al 2015) and molecular behaviors (Taylor et al 2016) have been observed when the same element is in the nanoscale phase, compared with the dissolved or larger particle phase. The composition of an inorganic NM appears to be an important property determining bioavailability and toxicity (S.N.…”

Nanomaterials in the aquatic environment: A European Union–United States perspective on the status of ecotoxicity testing, research priorities, and challenges ahead

“…Furthermore, most published papers seem biased toward pelagic organisms, with fewer studies on benthic organisms. Of the benthic studies, the freshwater oligochaete Lumbriculus variegatus and insect larva Chironomus riparius and the estuarine polychaetes Capitella teleta and Nereis diversicolor have been the focus of some sedimentary studies [6][7][8][9][10][11][12][13][14].…”

“…Most of these studies have reported total body burden after the conclusion of the experiment, while only a limited number have focused on uptake and depuration kinetics and NM transformations in the organisms [8,9,14,16,17,27,36,38,39]. Most likely as a result of limitations in availability of analytical methods and instruments, even fewer studies have been published on internal distribution of NMs after exposure [6,24,35,40], or on trophic transfer [27,37]. A weight of evidence is needed with different NMs and organisms to confirm the utility of simple body burden measurements for NMs and the theoretical basis (uptake mechanism, rate-limiting steps, etc.)…”

Trophic transfer of metal-based nanoparticles in aquatic environments: a review and recommendations for future research focus

“…Due to the increasing production and use of Me-ENPs, their release into the aquatic environment is inevitable and has already been demonstrated. 12,13 Several studies show that metals introduced to organisms as ENPs are taken up from the abiotic compartments from both water and diet, [14][15][16][17] commonly with ENPs mixed into sediments [18][19][20][21][22] Since 1991, she has been employed at DHI as a consultant and a researcher within the field of environmental fate, especially transformation as well as the hazardous effect of chemical substances, which also includes particulate pollutants such as nanoparticles and microplastics.…”