Bioactive and Biocompatible Nature of Green Synthesized Zinc Oxide Nanoparticles from Simarouba glauca DC.: An Endemic Plant to Western Ghats, India

Genotoxic and Cytotoxic Properties of Zinc Oxide Nanoparticles Phyto-Fabricated from the Obscure Morning Glory Plant Ipomoea obscura (L.) Ker Gawl

“…The radical scavenging activity (RSA) of phyto-fabricated ZnO-NPs was performed by following the method of Hemanth Kumar et al [5]. In brief, 3.5 mL of 0.1 mM DPPH containing 0.2, 0.4, 0.6, 0.8, and 1 mg mL −1 concentrations of ZnO-NPs were sonicated before incubating for 30 min at 37 ± 2 • C (under dark conditions) and the absorbance was measured at 517 nm in a spectrophotometer.…”

“…Nanoparticles have gained importance due to their surface area to volume ratio and the behaviors that result from that [1,2]. In light of the environmental and biological risks due to the toxicity of used chemicals in synthetic metal-oxide nanoparticles, biologically synthesized nanoparticles have gained considerable importance as they are considered to be stable, eco-friendly, and also possess biological properties [3][4][5][6]. Different methods have been employed for the synthesis of nanoparticles, of which the hydrothermal method is one of the alternatives to the synthetic methods, as it is simple, cost-effective, eco-friendly, and less hazardous [7][8][9].…”

“…It has been well documented in the literature that the chemical synthesis of nanoparticles yields toxic byproducts that are not eco-friendly and cost-effective, and researchers are concentrating on alternative methods [4][5][6]. Biosynthesis of nanoparticles using plant extract has gained interest due to its abundance of sources available in the environment [8,9].…”

“…In the recent past, ZnO-NPs have been synthesized from every part of the plant, such as leaves [8], stem [15], tuber [16], root [14], flower [7], fruit [17], and seed [18]. They have also shown to possess many biological properties such as antioxidant, antimicrobial, genotoxicity, cytotoxicity, etc., thereby indicating the efficacy toward their application in the field of pharmaceuticals [5,8,9,14,15]. The toxicity of chemically synthesized nanoparticles has paved the way for plant-mediated biosynthesis of nanoparticles due to their stable and eco-friendly nature in addition to their enhanced biological properties compared to chemically synthesized nanoparticles [2,5,8,9].…”

Biosynthesized ZnO-NPs from Morus indica Attenuates Methylglyoxal-Induced Protein Glycation and RBC Damage: In-Vitro, In-Vivo and Molecular Docking Study

“…The FT-IR spectroscopic analysis was carried out to recognize the functional groups in plant extracts, which play a vital role in the processes of reduction and stabilization of the biosynthesis of nanoparticles [37]. The biosynthesized ZnO-NPs bared a peak at 562.54 cm −1 which matches to metal oxide (M-O) bond which was absent in plant extract confirming that the extract acted as capping agents during the synthesis of nanoparticles [38,39]. In-plant extract, spectrum bands were observed at 3346.…”