Bioactive ceramic-based materials: beneficial properties and potential applications in dental repair and regeneration

Wang, Jiale; Zhang, Linglin; Wang, Kun

doi:10.1080/17460751.2024.2343555

Regenerative Medicine

2024

DOI: 10.1080/17460751.2024.2343555

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Bioactive ceramic-based materials: beneficial properties and potential applications in dental repair and regeneration

Jiale Wang,

Linglin Zhang,

Kun Wang

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2024

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Cited by 1 publication

References 241 publications

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Pulpal Responses to Leukocyte- and Platelet-Rich Plasma Treatment in Mouse Models for Immediate and Intentionally Delayed Tooth Replantation

Quispe-Salcedo,

Suzuki-Barrera,

Zapata-Sifuentes

et al. 2024

Applied Sciences

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This study aimed to evaluate the effect of leukocyte and platelet-rich plasma (L-PRP) on the pulpal healing process following immediate and intentionally delayed tooth replantation in mice. After the maxillary first molars of 3-week-old mice were extracted, the teeth were immersed for 1 min [immediate reimplantation (IR)] or 30 min [intentionally delayed reimplantation (IDR)] in phosphate-buffered saline (PBS) solution. The alveolar socket was filled with or without 1.5 μL of L-PRP [experimental or control groups (EG or CG)] followed by tooth replantation. Samples were collected from day 1 to week 4 after the operation, processed for histology, and evaluated by immunohistochemistry for Nestin and Ki-67 expression. Quantitative analysis revealed positive Nestin staining during pulpal healing in the EG at week 1 following IR and week 2 following IDR. Hard tissue deposition was significantly increased in the EG after IR at week 2. Cell proliferation was higher in the EG compared with that in the CG at week 1 and significantly decreased in the coronal pulp of the EG after the IDR at week 2. Our data suggest that treatment with L-PRP may have a positive effect on pulpal healing, even in teeth replanted after an extended extra-oral period.

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Pulpal Responses to Leukocyte- and Platelet-Rich Plasma Treatment in Mouse Models for Immediate and Intentionally Delayed Tooth Replantation

Quispe-Salcedo,

Suzuki-Barrera,

Zapata-Sifuentes

et al. 2024

Applied Sciences

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show abstract

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Bioactive ceramic-based materials: beneficial properties and potential applications in dental repair and regeneration

Cited by 1 publication

References 241 publications

Pulpal Responses to Leukocyte- and Platelet-Rich Plasma Treatment in Mouse Models for Immediate and Intentionally Delayed Tooth Replantation

Pulpal Responses to Leukocyte- and Platelet-Rich Plasma Treatment in Mouse Models for Immediate and Intentionally Delayed Tooth Replantation

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