Bioactive compounds in lettuce: Highlighting the benefits to human health and impacts of preharvest and postharvest practices

Yang, Xiao; Gil, M.V.; Yang, Qichang; Tomás‐Barberán, Francisco A

doi:10.1111/1541-4337.12877

Cited by 80 publications

(43 citation statements)

References 154 publications

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“…On the whole, probiotics – especially lactic acid bacteria and Bifidobacterium are considered to be safe supplements for healthy individuals of all ages, [ 26 ] and comprise a successful adjuvant therapy for cancer patients. [ 38,39 ] However, we note that some studies have reported adverse effects experienced by immunocompromised people following probiotic administration, such as excessive immune stimulation, infection (i.e., endocarditis and bacteremia), transmigration of pathogenic bacteria, and transfer of antibiotic resistance from probiotics to pathogenic bacteria (e.g., Tetracycline resistance among Lactobacillus Plantarum , Vancomycin resistance across many lactobacilli strains).…”

Section: General Overview Of Pro‐ and Prebiotics And Safety Issues Of...mentioning

confidence: 99%

Intake of Pro‐ and/or Prebiotics as a Promising Approach for Prevention and Treatment of Colorectal Cancer

Wang

Chen

Ning

et al. 2023

Molecular Nutrition Food Res

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Colorectal cancer (CRC) is the third most common type of cancer, posing a serious threat to human life. It is widely believed that dietary factors may be crucial modifiers of CRC risk, with pro‐and/or prebiotics being especially promising. In this review, a synthesis of CRC prevention and treatment of strategies relying on usage of pro‐ and/or prebiotics supplements is given, as well as discuss mechanisms underlying the contribution of pro‐and/or prebiotics to the suppression of colonic carcinogenesis. Furthermore, a framework for personalizing such supplements according to the composition of an individual's gut microbiome is suggested. Various factors including diversity of one's intestinal microflora, integrity of their intestinal barrier, and the presence of mutagenic/carcinogenic/genotoxic and beneficial compounds are known to have a prominent influence on the development of CRC; thus, clarifying the role of pro‐ and/or prebiotics will yield valuable insight toward optimizing interventions for enhanced patient outcomes in the future.

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Section: General Overview Of Pro‐ and Prebiotics And Safety Issues Of...mentioning

confidence: 99%

Intake of Pro‐ and/or Prebiotics as a Promising Approach for Prevention and Treatment of Colorectal Cancer

Wang

Chen

Ning

et al. 2023

Molecular Nutrition Food Res

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“…Agronomic management has been widely used to regulate the quality of vegetables (Yang et al, 2021). Current studies indicate that the method and timing of application of Se fertilizers, mineral elements in the rhizosphere, and external conditions affect the levels of Se-AAs in various plant species, though only a few studies have investigated these factors in vegetables.…”

Section: Agronomic Managementmentioning

confidence: 99%

Seleno-Amino Acids in Vegetables: A Review of Their Forms and Metabolism

Wang

Zhang

et al. 2022

Front. Plant Sci.

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Seleno-amino acids are safe, health-promoting compounds for humans. Numerous studies have focused on the forms and metabolism of seleno-amino acids in vegetables. Based on research progress on seleno-amino acids, we provide insights into the production of selenium-enriched vegetables with high seleno-amino acids contents. To ensure safe and effective intake of selenium, several issues need to be addressed, including (1) how to improve the accumulation of seleno-amino acids and (2) how to control the total selenium and seleno-amino acids contents in vegetables. The combined use of plant factories with artificial lighting and multiple analytical technologies may help to resolve these issues. Moreover, we propose a Precise Control of Selenium Content production system, which has the potential to produce vegetables with specified amounts of selenium and high proportions of seleno-amino acids.

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“…Lettuce is rich in water with 94–95% content and low in calories. It is also an excellent source of vitamins, minerals, and bioactive compounds such as polyphenols, carotenoids, and chlorophyll with related health benefits [ 3 ]. Additionally, phytochemical compositions and contents are different in various types.…”

Section: Introductionmentioning

confidence: 99%

Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce—A Comprehensive Review

Shi

et al. 2022

Antioxidants

101

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Lettuce is one of the most famous leafy vegetables worldwide with lots of applications from food to other specific uses. There are different types in the lettuce group for consumers to choose from. Additionally, lettuce is an excellent source of bioactive compounds such as polyphenols, carotenoids, and chlorophyll with related health benefits. At the same time, nutrient composition and antioxidant compounds are different between lettuce varieties, especially for green and red lettuce types. The benefit of lettuce consumption depends on its composition, particularly antioxidants, which can function as nutrients. The health benefits rely on their biochemical effect when reaching the bloodstream. Some components can be released from the food matrix and altered in the digestive system. Indeed, the bioaccessibility of lettuce is measuring the quantity of these compounds released from the food matrix during digestion, which is important for health-promoting features. Extraction of bioactive compounds is one of the new trends observed in lettuce and is necessarily used for several application fields. Therefore, this review aims to demonstrate the nutritional value of lettuce and its pharmacological properties. Due to their bioaccessibility and bioavailability, the consumer will be able to comprehensively understand choosing a healthier lettuce diet. The common utilization pattern of lettuce extracted nutrients will also be summarized for further direction.

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Bioactive compounds in lettuce: Highlighting the benefits to human health and impacts of preharvest and postharvest practices

Cited by 80 publications

References 154 publications

Intake of Pro‐ and/or Prebiotics as a Promising Approach for Prevention and Treatment of Colorectal Cancer

Intake of Pro‐ and/or Prebiotics as a Promising Approach for Prevention and Treatment of Colorectal Cancer

Seleno-Amino Acids in Vegetables: A Review of Their Forms and Metabolism

Phytochemicals, Nutrition, Metabolism, Bioavailability, and Health Benefits in Lettuce—A Comprehensive Review

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