Bioactive compounds of corn silk and their role in management of glycaemic response

Singh, Jyoti; Rasane, Prasad; Nanda, Vikas; Kaur, Sawinder

doi:10.1007/s13197-022-05442-z

Cited by 21 publications

(10 citation statements)

References 41 publications

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“…Therefore, searching for effective and safe drugs is a research hotspot. In recent years, with the development of corn silk, antihypertensive activity has caught researchers’ attention [ 5 , 89 ]. The aqueous extract of corn silk at doses of 60 mg/kg, 130 mg/kg, 192.5 mg/kg, and 260 mg/kg showed a specific dose-dependent antihypertensive effect [ 90 ].…”

Section: Pharmacological Actionsmentioning

confidence: 99%

“…Studies of its phytochemical and pharmacological properties have become hot topics. According to reports in the literature, there are a variety of chemical components in corn silk, covering macromolecular polysaccharides [ 4 ] and various micromolecular components [ 5 ], like saponins, flavonoids, sterols, amino acids, terpenes, and organic acids. Furthermore, in modern clinics, corn silk is applied to treat various diseases, such as nephritis, acute and chronic pneumonia, diabetes, hypertension, and edema [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An Umbrella Insight into the Phytochemistry Features and Biological Activities of Corn Silk: A Narrative Review

Wang,

Mao,

Zhang

et al. 2024

Molecules

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Corn silk (Zea mays L.) is the stigma of an annual gramineous plant named corn, which is distributed in many regions worldwide and has a long history of medicinal use. In recent years, with the sustainable development of traditional Chinese medicine, studies of corn silk based on modern technologies, such as GC–MS, LC–MS, and other analytical means, have offered more comprehensive analyses. Phytochemistry studies have shown that the main bioactive components in corn silk include flavonoids, polyphenols, phenolic acids, fatty acids, and terpenoids. Pharmacological studies have shown that corn silk extract has various pharmacological effects, such as reducing blood lipids, lowering blood pressure, regulating blood sugar levels, anti-inflammatory effects, and anti-oxidation effects. In this paper, the related research on corn silk from the past few years is summarized to provide a theoretical reference for the further development and utilization of corn silk.

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Section: Pharmacological Actionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

An Umbrella Insight into the Phytochemistry Features and Biological Activities of Corn Silk: A Narrative Review

Wang,

Mao,

Zhang

et al. 2024

Molecules

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“…Corn silk, another by-product from corn processing, contains a wide range of bioactive compounds in the form of volatile oils, steroids, saponins, anthocyanins [ 59 ], and other natural antioxidants, such as flavonoids [ 52 ] and phenolic compounds [ 41 , 58 , 59 ]. In the corn silk powder, the high phenolic content (94.10 ± 0.26 mg GAE/g) and flavonoid content (163.93 ± 0.83 mg QE/100 g) are responsible for its high antioxidant activity [ 60 ]. About 29 flavonoids have been isolated from corn silk.…”

Section: Phytochemicals From Crop Residuesmentioning

confidence: 99%

Phytochemicals Derived from Agricultural Residues and Their Valuable Properties and Applications

et al. 2023

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Billions of tons of agro-industrial residues are produced worldwide. This is associated with the risk of pollution as well as management and economic problems. Simultaneously, non-edible portions of many crops are rich in bioactive compounds with valuable properties. For this reason, developing various methods for utilizing agro-industrial residues as a source of high-value by-products is very important. The main objective of the paper is a review of the newest studies on biologically active compounds included in non-edible parts of crops with the highest amount of waste generated annually in the world. The review also provides the newest data on the chemical and biological properties, as well as the potential application of phytochemicals from such waste. The review shows that, in 2020, there were above 6 billion tonnes of residues only from the most popular crops. The greatest amount is generated during sugar, oil, and flour production. All described residues contain valuable phytochemicals that exhibit antioxidant, antimicrobial and very often anti-cancer activity. Many studies show interesting applications, mainly in pharmaceuticals and food production, but also in agriculture and wastewater remediation, as well as metal and steel industries.

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“…In multiple ancient books and local standards of Chinese medicinal materials, corn silk was recorded with multiple effects like diuretic and detumescent, liver and gallbladder protection. Modern pharmacological studies showed that corn silk could be anti‐diabetic [1, 2], anti‐hyperuricemia [3], anti‐oxidant [4], anti‐cancer [5], anti‐obesity [6], anti‐inflammatory [7], lowering blood lipids [8], improving sleep disorders, etc. [9].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical study: Fragmentation patterns of flavonoid‐C‐glycosides in the enriched flavonoids from corn silk using high‐efficiency ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

Wang,

Gu,

Mao

et al. 2023

Separation Science Plus

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Flavonoid‐C‐glycosides with various pharmacological actions were abundant in corn silk, and fragmentation in mass spectra of flavonoid‐C‐glycosides compounds was particularly important. This paper aimed to supervise the fragmentation patterns of flavonoid‐C‐glycosides in the enriched flavonoids from corn silk by high‐efficiency ultra‐high‐performance liquid chromatography combined with a quadrupole time‐of‐flight mass spectrometry approach. Therefore, the flavonoids were extracted by heating reflux and then purified based on D101 macroporous resin. Thirty‐five flavonoids were triumphantly identified in the purified product. Among them, 14 were flavonoid‐C‐glycosides, seven of them owned luteolin mother nuclei (luteolin‐C‐glycosides) and seven of them owned apigenin mother nuclei (apigenin‐C‐glycosides). Importantly, the diagnostic product ions of luteolin‐C‐glycosides including m/z (431, 413, 395, 369, 367, 313, and 299) and m/z (429, 411, 393, 367, 365, 311, and 297), and the characteristic product ions of apigenin‐C‐glycosides covered m/z (353, 339, and 299) and m/z (339, 327, and 309). In addition, diagnostic H2O neutral loss and glycosyl craking were familiar, and the difference values among product ions mainly contained 40, 60, 70, 80, 90, 100, and 120 Da. Thus, the fragmentations of luteolin‐C‐glycosides and apigenin‐C‐glycosides identified in corn silk were with proper regularity. The obtained fragmentation patterns provided rapid recognition and meaningful guidance for the purification study of flavonoid‐C‐glycosides.

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Bioactive compounds of corn silk and their role in management of glycaemic response

Cited by 21 publications

References 41 publications

An Umbrella Insight into the Phytochemistry Features and Biological Activities of Corn Silk: A Narrative Review

An Umbrella Insight into the Phytochemistry Features and Biological Activities of Corn Silk: A Narrative Review

Phytochemicals Derived from Agricultural Residues and Their Valuable Properties and Applications

Phytochemical study: Fragmentation patterns of flavonoid‐C‐glycosides in the enriched flavonoids from corn silk using high‐efficiency ultra‐high‐performance liquid chromatography combined with quadrupole time‐of‐flight mass spectrometry

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