Bioactive Dental Resin Composites with MgO Nanoparticles

Wang, Yuan; Wu, Zhongyuan; Wang, Ting; Tang, Weilong; Li, Ting‐Ting; Xu, Haiping; Sun, Hui; Lin, Yifan; Tonin, Bruna Santos Honório; Ye, Zhou; Fu, Jing

doi:10.1021/acsbiomaterials.3c00490

Cited by 9 publications

(5 citation statements)

References 77 publications

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“…Therefore, it has been incorporated as an antibacterial filler into resin composites, dental cement, and glass-ionomer cement, to prevent secondary caries formation [ 45 , 46 ]. At low concentrations (2-7.5% by weight), this addition was found to greatly enhance anti-biofilm properties without compromising their mechanical, physicochemical, or biocompatibility properties [ 47 , 48 ]. Furthermore, it's possible that a minimum quantity of MgO nanoparticles improved resin composite polymerization and enhanced the depth of curing, as well as decelerating the aging process of the material [ 47 , 48 ].…”

Section: Reviewmentioning

confidence: 99%

“…At low concentrations (2-7.5% by weight), this addition was found to greatly enhance anti-biofilm properties without compromising their mechanical, physicochemical, or biocompatibility properties [ 47 , 48 ]. Furthermore, it's possible that a minimum quantity of MgO nanoparticles improved resin composite polymerization and enhanced the depth of curing, as well as decelerating the aging process of the material [ 47 , 48 ]. This could be a useful tool in the development of antibacterial resin composites to prevent secondary caries formation.…”

Section: Reviewmentioning

confidence: 99%

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Antibacterial Agents for Composite Resin Restorative Materials: Current Knowledge and Future Prospects

Algarni

2024

Cureus

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Resin composites became the material of choice for direct restorations in anterior and posterior teeth. Despite the revolutionary improvement in the material, restoration failure is still a major drawback due to the material’s inherent negative properties, including a lack of antibacterial effects. Therefore, many attempts have been made to incorporate antibacterial agents into resin composite materials to improve their antimicrobial properties and prevent secondary caries formation. Multiple laboratory studies have been conducted using different antibacterial agents, such as quaternary ammonium compounds, methacryloyloxydodecylpyridinium bromide, magnesium oxide nanoparticles, chlorhexidine, and chitosan. This review provides a glance at the current status of these materials and the research directions needed in the future.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Antibacterial Agents for Composite Resin Restorative Materials: Current Knowledge and Future Prospects

Algarni

2024

Cureus

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“…In addition, there was a study on the addition of DMAHDM, NACP and microcapsules to dental adhesive resins [ 86 ]. Via experimental confirmation, a new antimicrobial resin adhesive with self-healing functions that could be used for clinical applications was developed [ 64 , 87 , 88 , 89 ].…”

Section: Applications Of Self-healing Microcapsules In Dental Compositesmentioning

confidence: 99%

A Review on the Current State of Microcapsule-Based Self-Healing Dental Composites

Wang,

Ding

2024

JFB

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Resin-based dental composites, commonly used in dentistry, offer several advantages including minimally invasive application, esthetically pleasing appearance, and good physical and mechanical properties. However, these dental composites can be susceptible to microcracks due to various factors in the complex oral environment. These microcracks can potentially lead to clinical restoration failure. Conventional materials and methods are inadequate for detecting and repairing these microcracks in situ. Consequently, incorporating self-healing properties into dental composites has become a necessity. Recent years have witnessed rapid advancements in self-healing polymer materials, drawing inspiration from biological bionics. Microcapsule-based self-healing dental composites (SHDCs) represent some of the most prevalent types of self-healing materials utilized in this domain. In this article, we undertake a comprehensive review of the most recent literature, highlighting key insights and findings related to microcapsule-based SHDCs. Our discussion centers particularly on the preparation techniques, application methods, and the promising future of self-healing microcapsules in the field of dentistry.

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“…In addition, the antimicrobial potential of Mg attributes underscores its significance in periodontal regeneration. [89][90][91]…”

Section: Magnesiummentioning

confidence: 99%

Ion incorporation into bone grafting materials

Zhao,

Ni,

Wei

et al. 2023

Periodontology 2000

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The use of biomaterials in regenerative medicine has expanded to treat various disorders caused by trauma or disease in orthopedics and dentistry. However, the treatment of large and complex bone defects presents a challenge, leading to a pressing need for optimized biomaterials for bone repair. Recent advances in chemical sciences have enabled the incorporation of therapeutic ions into bone grafts to enhance their performance. These ions, such as strontium (for bone regeneration/osteoporosis), copper (for angiogenesis), boron (for bone growth), iron (for chemotaxis), cobalt (for B12 synthesis), lithium (for osteogenesis/cementogenesis), silver (for antibacterial resistance), and magnesium (for bone and cartilage regeneration), among others (e.g., zinc, sodium, and silica), have been studied extensively. This review aims to provide a comprehensive overview of current knowledge and recent developments in ion incorporation into biomaterials for bone and periodontal tissue repair. It also discusses recently developed biomaterials from a basic design and clinical application perspective. Additionally, the review highlights the importance of precise ion introduction into biomaterials to address existing limitations and challenges in combination therapies. Future prospects and opportunities for the development and optimization of biomaterials for bone tissue engineering are emphasized.

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Bioactive Dental Resin Composites with MgO Nanoparticles

Cited by 9 publications

References 77 publications

Antibacterial Agents for Composite Resin Restorative Materials: Current Knowledge and Future Prospects

Antibacterial Agents for Composite Resin Restorative Materials: Current Knowledge and Future Prospects

A Review on the Current State of Microcapsule-Based Self-Healing Dental Composites

Ion incorporation into bone grafting materials

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