2019
DOI: 10.3390/cosmetics6010007
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Bioactive Metabolites of the Stem Bark of Strychnos aff. darienensis and Evaluation of Their Antioxidant and UV Protection Activity in Human Skin Cell Cultures

Abstract: The genus Strychnos (Loganiaceae) is well-known as a rich source of various bioactive metabolites. In continuation of our phytochemical studies on plants from Amazonia, we examined Strychnosaff. darienensis, collected in Peru. This species has been traditionally used in South America and is still presently used as a drug by the Yanesha tribe in Peru. Phytochemical investigation of this plant led to the isolation and structure elucidation by ΝuclearΜagnetic Resonance and High Resolution Mass Spectroscopy of 14 … Show more

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Cited by 3 publications
(3 citation statements)
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“…Many studies are investigating different kinds of fruits, vegetables, and plant extracts as an antioxidant for reducing the risk of the diseases caused by free radicals [20][21][22]. Strychnobiflavone was previously used as an anti-leishmanial and anti-aging [23][24]. The structure of strychnobiflavone contains phenolic and flavonoid functional groups.…”
Section: ■ Introductionmentioning
confidence: 99%
“…Many studies are investigating different kinds of fruits, vegetables, and plant extracts as an antioxidant for reducing the risk of the diseases caused by free radicals [20][21][22]. Strychnobiflavone was previously used as an anti-leishmanial and anti-aging [23][24]. The structure of strychnobiflavone contains phenolic and flavonoid functional groups.…”
Section: ■ Introductionmentioning
confidence: 99%
“…Travasarou et al in their article describe the isolation and structure elucidation of bioactive metabolites from the Amazonian plant Strychnos aff. darienensis, mostly known for its toxic alkaloids, traditionally used in the preparation of the deadly curare [4]. This novel approach, however, focuses on this plant's flavonoids, which possess significant antioxidant activities for dermal cells, while two of them-luteolin and strychnobiflavone-confer also photoprotection; hence, they can be used as bioactive ingredients in the cosmetic industry [4].…”
mentioning
confidence: 99%
“…darienensis, mostly known for its toxic alkaloids, traditionally used in the preparation of the deadly curare [4]. This novel approach, however, focuses on this plant's flavonoids, which possess significant antioxidant activities for dermal cells, while two of them-luteolin and strychnobiflavone-confer also photoprotection; hence, they can be used as bioactive ingredients in the cosmetic industry [4]. Li et al, on the other hand, report on an extract from a completely different source, namely the marine brown seaweed Sargassum glaucescens, one of the most abundant species of algae on the rocky coasts of Taiwan [5].…”
mentioning
confidence: 99%