Bioactive Phytoconstituents of Morus Plants exhibiting Numerous Therapeutic Activities

Abstract

Morus is a plant genus of the family Moraceae, most of which is used as a decoction in traditional medicines for the treatment of cough, bronchitis, pulmonary diseases and reduces the plasma sugar level. Many studies in Morus phytochemistry have contributed to the discovery of Diels-Alder-type adducts, arylbenzofurans, and flavonoids with antioxidant, antihyperglycemic, antihypertensive, antihyperlipidemic, and anti-inflammatory activities. The purpose of this article was to offers an account of the updated knowledge on the phytochemicals and pharmacological activities of these compounds. This review will help to fully understanding the efficacy and pave the way for further explore the comprehensive use of Morus. We conclude that Morus needs further reports in the identification of bioactive constituents and strengthen the claim of folk medicines.

Interleukin-10 as Covid-19 biomarker targeting KSK and its analogues: Integrated network pharmacology

“…Mulberrofuran W is a bioactive compound present in the Morus plant. It has anti-hyperglycemic activity via inhibiting the tyrosine phosphatase and anti-carcinogenic activity via inhibiting the hypoxia-activated HIF-1 α [ 51 ].…”

The Efficacy of Alcoholic Extracts of Morus Macroura (Mulberries), Lepidium Sativum (Garden Cress Seeds) and Diclazuril Against E. stiedae in Experimentally Infected Rabbits

“…Such effect may attributed to M. macroura's bioactive components such as flavonoids and phenolic acids, which were previously shown to have an assortment of beneficial therapeutic effects (Nile and Park 2014;Skrovankova et al 2015;El-Haddad et al 2021;Memete et al 2022). These dietary polyphenolic compounds have been proven to have antioxidant and anti-inflammatory activity.…”